Hydrogels are water-swollen three-dimensional networks made of polymers, proteins, small
molecules or colloids. They constitute a versatile platform for drug delivery because of their …

As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …

Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …

Owing to the distinctive constituents of tumor tissue from those healthy organs,
nanomedicine strategies show significant potentials in smart drug delivery. Nowadays …

Polymer nanogels (NGs) are water-swellable, cross-linked 3D network structures with size
typically range from 1 to 1000 nm. Especially, biocompatible and “smart” NGs engineered …

In recent years, polymer nanoassemblies have played an important role in the
biopharmaceuticals field. Polymers that form different molecular architectures during a self …

In this study, we developed novel hyaluronic acid cross-linked zein nanogels (HA-Zein NGs)
to deliver the potential anticancer agent curcumin (CRC), a naturally occurring …

Stimuli-responsive microcapsules, which can release the encapsulated payload under
various environmental stimuli, have attracted great interests of the food, pharmaceutical …

Zein is a kind of excellent carrier materials to construct nano-sized delivery systems for
hydrophobic bioactives, owing to its unique interfacial behavior, such as self-assembly and …

Here a novel photo, pH, and redox triple-responsive nanogel of poly (acrylic acid-co-
spiropyran methacrylate) crosslinked by disulfide-containing N, N-bis (acryloyl) cystamine …