Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy

H Niu, J Liu, HM O'Connor, T Gunnlaugsson… - Chemical Society …, 2023 - pubs.rsc.org
Typical PeT-based fluorescent probes are multi-component systems where a fluorophore is
connected to a recognition/activating group by an unconjugated linker. PeT-based …

The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

HH Han, HM Wang, P Jangili, M Li, L Wu… - Chemical Society …, 2023 - pubs.rsc.org
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Fluorescence imaging of pathophysiological microenvironments

S Wang, WX Ren, JT Hou, M Won, J An… - Chemical Society …, 2021 - pubs.rsc.org
Abnormal microenvironments (viscosity, polarity, pH, etc.) have been verified to be closely
associated with numerous pathophysiological processes such as inflammation …

Coumarin-based small-molecule fluorescent chemosensors

D Cao, Z Liu, P Verwilst, S Koo, P Jangjili… - Chemical …, 2019 - ACS Publications
Coumarins are a very large family of compounds containing the unique 2 H-chromen-2-one
motif, as it is known according to IUPAC nomenclature. Coumarin derivatives are widely …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Sulfur-based fluorescent probes for HOCl: Mechanisms, design, and applications

JT Hou, N Kwon, S Wang, B Wang, X He, J Yoon… - Coordination Chemistry …, 2022 - Elsevier
Hypochlorous acid (HOCl) is an endogenously produced reactive oxygen species (ROS),
which acts as a protector against microbes. However, its aberrant production is implicated in …

Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Natural flavylium-inspired far-red to NIR-II dyes and their applications as fluorescent probes for biomedical sensing

Y Sun, P Sun, Z Li, L Qu, W Guo - Chemical Society Reviews, 2022 - pubs.rsc.org
Fluorescent probes that emit in the far-red (600–700 nm), first near-infrared (NIR-I, 700–900
nm), and second NIR (NIR-II, 900–1700 nm) regions possess unique advantages, including …