Orthopedic implants are increasing in global prevalence, with hundreds of thousands of
operations performed annually. However, a significant proportion of these operations …

Surface biofunctionalization aims to create cell-instructive surfaces that control the behavior
of cells and modulate cellular interactions by incorporating cell signaling moieties at the …

Block polymers have undergone extraordinary evolution since their inception more than 60
years ago, maturing from simple surfactants to an expansive class of macromolecules …

Native arteries contain a distinctive intima‐media composed of organized elastin and an
adventitia containing mature collagen fibrils. In contrast, implanted biodegradable small …

Immobilizing a protein, that is fully compatible with the patient, on the surface of a biomedical
device should make it possible to avoid adverse responses such as inflammation, rejection …

The development of vascular grafts has focused on finding a biomaterial that is non-
thrombogenic, minimizes intimal hyperplasia, matches the mechanical properties of native …

Surface functionalization of an implantable device with bioactive molecules can overcome
adverse biological responses by promoting specific local tissue integration. Bioactive …

The short‐and long‐term thrombogenicity of implant materials is still unpredictable, which is
a significant challenge for the treatment of cardiovascular diseases. A knowledge‐based …

Coated layers of biologically active molecules on synthetic biomaterials and biomedical
devices can promote a variety of desirable biological reactions by the host body or the …

Despite major research efforts in the field of biomaterials, rejection, severe immune
responses, scar tissue and poor integration continue to seriously limit the performance of …