Protein kinase CK2 is a pleiotropic, ubiquitous and constitutively active protein kinase that
can use both ATP and GTP as phosphoryl donors with specificity for serine/threonine …

Since the first generation of a negative-sense RNA virus entirely from cloned cDNA in 1994,
similar reverse genetics systems have been established for members of most genera of the …

Subgenomic selectable RNAs of the hepatitis C virus (HCV) have recently been shown to
self-replicate to high levels in the human hepatoma cell line Huh-7 (V. Lohmann, F. Körner …

We have reported that ceramide mediates binding of atypical protein kinase C (PKC) ζ to its
inhibitor protein, PAR-4 (prostate apoptosis response-4), thereby inducing apoptosis in …

ABSTRACT NS5A of the hepatitis C virus (HCV) is a highly phosphorylated protein involved
in resistance against interferon and required most likely for replication of the viral genome …

NS5A derived from a hepatitis C virus (HCV) genotype 1b isolate has previously been
shown to undergo phosphorylation on serine residues (T. Kaneko, Y. Tanji, S. Satoh, M …

Protein Kinase C (PKC) is a family of serine–threonine kinases found in most cell types
whose activity has a strong influence on a wide variety of signal transduction events …

Viral infection is the primary cause of respiratory morbidity in cystic fibrosis (CF) infants.
Here, we identify that host factors allow increased virus replication and cytokine production …

Influenza virus expresses transcripts early in infection and transitions towards genome
replication at later time points. This process requires de novo assembly of the viral …

A full-length clone of the human parainfluenza virus type 3 (HPIV-3) genome (called pHPIV-
3) was constructed, and recombinant, infectious HPIV-3 was generated by transfecting …