Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

In recent years, obesity and its associated health disorders and costs have increased.
Accumulation of adipose tissue, or fat, in the intra-abdominal adipose depot is associated …

The finding of orexin/hypocretin deficiency in narcolepsy patients suggests that this
hypothalamic neuropeptide plays a crucial role in regulating sleep/wakefulness states …

Background Brainstem-focused mechanisms supporting transcutaneous auricular VNS
(taVNS) effects are not well understood, particularly in humans. We employed ultrahigh field …

Drugs activating 5-hydroxytryptamine 2C receptors (5-HT 2C Rs) potently suppress appetite,
but the underlying mechanisms for these effects are not fully understood. To tackle this …

The median (MR) and dorsal raphe (DR) nuclei contain the majority of the 5-
hydroxytryptamine (5-HT, serotonin) neurons that project to limbic forebrain regions, are …

Serotonergic systems play an important role in the regulation of behavioural, autonomic and
endocrine responses to stressful stimuli. This includes modulation of both the hypothalamic …

This communication provides an update of our understanding of the neurological bases for
the close association between balance control and anxiety. New data suggest that a …

Anxiety is a complex emotional state associated with sustained heightened autonomic and
behavioral arousal and an increase in avoidance behavior. Anxiety-related behavior is a …

The dorsal raphe nucleus (DRN) is an important nucleus in pain modulation. It has abundant
5-HT neurons and many other neurotransmitter and/or neuromodulator containing neurons …