Nuclear factor-kappaB (NF-ĸB) plays a crucial role in both innate and adaptive immune
systems, significantly influencing various physiological processes such as cell proliferation …

Circadian clocks participate in the coordination of various metabolic and biological activities
to maintain homeostasis. Disturbances in the circadian rhythm and cancers are closely …

Sclerosing epithelioid fibrosarcoma (SEF) is an aggressive soft tissue sarcoma. In the
majority of cases, there is overexpression of MUC4, and most cases show EWSR1 …

Metabolic rewiring offers novel therapeutic opportunities in cancer. Until recently, there was
scant information regarding soft tissue sarcomas, due to their heterogeneous tissue origin …

High-grade sarcomas are metastatic and pose a serious threat to patient survival.
Undifferentiated pleomorphic sarcoma (UPS) is a particularly dangerous and relatively …

Radiotherapy is an important means of tumor treatment, but radiotherapy resistance has
been a difficult problem in the comprehensive treatment of clinical tumors. The mechanisms …

ABSTRACT Objectives Long non‐coding RNAs (lncRNAs) are extensively reported as
participants in the biological process of diverse malignancies, including lung squamous cell …

Glycyrrhizin (GL), an important active ingredient of licorice root, which weakens the
proinflammatory effects of high-mobility group box 1 (HMGB1) by blocking HMGB1 …

We first reported that the Hippo-YAP signaling pathway plays a critical role in the
pathogenesis of endometriosis (EMS). Autophagy is also related to the invasion ability of …

Although recent advances in cancer treatment significantly improved the prognosis of
patients, drug resistance remains a major challenge. Targeting programmed cell death is a …