Objective To summarize the application of non-targeted metabolomics in epidemiological
studies that assessed metabolite and metabolic pathway alterations associated with per-and …

Evidence shows that herbal medicine (HM) could be beneficial for the treatment of various
diseases. However, complexities present in HM due to the unclear bioactive compounds …

Metabolomics provides a comprehensive assessment of numerous small molecules in
biological samples. As it integrates the effects of exogenous exposures, endogenous …

Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Dioxane has historically been used to stabilize chlorinated solvents and more recently has
been found as a contaminant of numerous consumer and food products. Once discharged …

Metabolomics is the study of metabolome within cells, biofluids, tissues, or organisms to
comprehensively identify and quantify all endogenous and exogenous low-molecular …

Altered central carbon metabolism is a hallmark of many diseases including diabetes,
obesity, heart disease and cancer. Identifying metabolic changes will open opportunities for …

Network-based approach is rapidly emerging as a promising strategy to integrate and
interpret different-omics datasets, including metabolomics. The first section of this chapter …

The scale at which MS‐and NMR‐based platforms generate metabolomics datasets for both
research, core, and clinical facilities to address challenges in the various sciences—ranging …

Perfluoroalkyl substances (PFAS) are widespread persistent environmental pollutants.
There is evidence that PFAS induce metabolic perturbations in humans, but underlying …