Systematic reviews of diagnostic test accuracy (DTA) studies are fundamental to the
decision making process in evidence based medicine. Although such studies are regarded …

Carcinoembryonic antigen (CEA) is not normally produced in significant quantities after birth
but is elevated in colorectal cancer. The aim of this review was to define the current role of …

Purpose: Detection of persistent circulating tumor DNA (ctDNA) after curative-intent surgery
can identify patients with minimal residual disease (MRD) who will ultimately recur. Most …

The incidence of rectal cancer in the European Union is $125 000 per year, ie $35% of the
total colorectal cancer incidence, reflecting 15–25 cases/100000 population per year and is …

Introduction Colorectal cancer is the fourth most common cancer in the UK. There remains a
need for improved risk stratification following curative resection. Circulating-tumour DNA …

Objective Mutations in cell-free circulating DNA (cfDNA) have been studied for tracking
disease relapse in colorectal cancer (CRC). This approach requires personalised assay …

Carcinoembryonic antigen (CEA), as one of the common tumor markers, is a human
glycoprotein involved in cell adhesion and is expressed during human fetal development …

The colorimetric lateral flow assay (CLFA, also known as test strip) is a widely used point-of-
care diagnostic technology. It has been a challenge to significantly improve the detection …

Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

Objective Current non-invasive early detection of colorectal cancer (CRC) requires
improvement. We aimed to identified a fecal Clostridium symbiosum-based biomarker for …