Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

KW Witwer, BWM Van Balkom, S Bruno… - Journal of …, 2019 - Taylor & Francis
Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are
transiting rapidly towards clinical applications. However, discrepancies and controversies …

Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy

X Li, AL Corbett, E Taatizadeh, N Tasnim, JP Little… - APL …, 2019 - pubs.aip.org
ABSTRACT Exosomes are small ($30–140 nm) lipid bilayer-enclosed particles of
endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …

Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small …

KS Visan, RJ Lobb, S Ham, LG Lima… - Journal of …, 2022 - Wiley Online Library
Small extracellular vesicles (sEVs) provide major promise for advances in cancer
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …

Nanoparticle characterization: what to measure?

MM Modena, B Rühle, TP Burg, S Wuttke - Advanced Materials, 2019 - Wiley Online Library
What to measure? is a key question in nanoscience, and it is not straightforward to address
as different physicochemical properties define a nanoparticle sample. Most prominent …

The methods of choice for extracellular vesicles (EVs) characterization

R Szatanek, M Baj-Krzyworzeka, J Zimoch… - International journal of …, 2017 - mdpi.com
In recent years, extracellular vesicles (EVs) have become a subject of intense study. These
membrane-enclosed spherical structures are secreted by almost every cell type and are …

Dynamic light scattering and transmission electron microscopy in drug delivery: a roadmap for correct characterization of nanoparticles and interpretation of results

SK Filippov, R Khusnutdinov, A Murmiliuk, W Inam… - Materials …, 2023 - pubs.rsc.org
In this focus article, we provide a scrutinizing analysis of transmission electron microscopy
(TEM) and dynamic light scattering (DLS) as the two common methods to study the sizes of …

The chemistry of reticular framework nanoparticles: MOF, ZIF, and COF materials

E Ploetz, H Engelke, U Lächelt… - Advanced Functional …, 2020 - Wiley Online Library
Nanoparticles have become a vital part of a vast number of established processes and
products; they are used as catalysts, in cosmetics, and even by the pharmaceutical industry …

[HTML][HTML] Measuring particle size distribution and mass concentration of nanoplastics and microplastics: addressing some analytical challenges in the sub-micron size …

F Caputo, R Vogel, J Savage, G Vella, A Law… - Journal of colloid and …, 2021 - Elsevier
Hypothesis The implementation of the proposal from the European Chemical Agency
(ECHA) to restrict the use of nanoplastics (NP) and microplastics (MP) in consumer products …

Characterisation of particles in solution–a perspective on light scattering and comparative technologies

CM Maguire, M Rösslein, P Wick… - … and technology of …, 2018 - Taylor & Francis
We present here a perspective detailing the current state-of-the-art technologies for the
characterisation of nanoparticles (NPs) in liquid suspension. We detail the technologies …

Making sense of Brownian motion: colloid characterization by dynamic light scattering

PA Hassan, S Rana, G Verma - Langmuir, 2015 - ACS Publications
Dynamic light scattering (DLS) has evolved as a fast, convenient tool for particle size
analysis of noninteracting spherical colloids. In this historical review, we discuss the basic …