Heated tobacco products: insights into composition and toxicity

S Upadhyay, M Rahman, G Johanson, L Palmberg… - Toxics, 2023 - mdpi.com
Heated tobacco products (HTPs) are novel products that allow users to inhale nicotine by
heating (350° C) reconstituted tobacco rather than combustion (900° C) as in conventional …

Immunology in COPD and the use of combustible cigarettes and heated tobacco products

J Błach, M Siedliński, W Sydor - European Journal of Medical Research, 2023 - Springer
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic
respiratory diseases, characterised by high morbidity and mortality. COPD is characterised …

Insight into the pulmonary molecular toxicity of heated tobacco products using human bronchial and alveolar mucosa models at air–liquid interface

M Rahman, M Irmler, M Introna, J Beckers… - Scientific Reports, 2022 - nature.com
Heated tobacco products (HTP) are novel nicotine delivery products with limited
toxicological data. HTP uses heating instead of combustion to generate aerosol (HTP …

The long-term effects of heated tobacco product exposure on the central nervous system in a mouse model of prodromal Alzheimer's disease

H Yamada, Y Yamazaki, Y Takebayashi, K Yazawa… - Scientific Reports, 2024 - nature.com
Heated tobacco products (HTPs) have emerged as novel alternatives to conventional
cigarettes (CCs), marketed by the tobacco industry as having a reduced potential for harm …

Comparative evaluation of ten blood biomarkers of inflammation in regular heated tobacco users and non-smoking healthy males–a pilot study

B Świątkowska, M Jankowski, D Kaleta - Scientific Reports, 2024 - nature.com
Heated tobacco products (HTPs) are novel tobacco products that are alternatives to
cigarettes. The study aimed to investigate the effect of HTPs on blood biomarkers of …

Increased oxidative stress and effects on inflammatory cytokine secretion by heated tobacco products aerosol exposure to mice

M Sawa, A Ushiyama, Y Inaba, K Hattori - Biochemical and Biophysical …, 2022 - Elsevier
Although the amount of chemicals in heated tobacco products (HTPs) aerosols is reduced
compared to conventional combustible cigarette smoke, the association between HTPs and …

Impact of heated tobacco products, e-cigarettes, and combustible cigarettes on small airways and arterial stiffness

I Goebel, T Mohr, PN Axt, H Watz, F Trinkmann… - Toxics, 2023 - mdpi.com
Smoking cessation is difficult but maintaining smoke-free without nicotine replacement
therapy is even harder. During the last few years, several different alternative products …

Not all vaping is the same: differential pulmonary effects of vaping cannabidiol versus nicotine

TA Bhat, SG Kalathil, ML Goniewicz, A Hutson… - Thorax, 2023 - thorax.bmj.com
Rationale Vaping has become a popular method of inhaling various psychoactive
substances. While evaluating respiratory effects of vaping have primarily focused on nicotine …

Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs

NA Nitta, T Sato, M Komura… - … of Physiology-Lung …, 2022 - journals.physiology.org
Pulmonary emphysema is predominantly caused by chronic exposure to cigarette smoke
(CS). Novel tobacco substitutes, such as heated tobacco products (HTPs), have emerged as …

Chronic exposure to IQOS results in impaired pulmonary function and lung tissue damage in mice

J Gu, D Gong, Y Wang, T Feng, J Zhang, S Hu, L Min - Toxicology Letters, 2023 - Elsevier
The use of IQOS brand heated tobacco products (HTPs) is increasing worldwide; however,
little is known about the long-term effects of HTPs aerosol exposure on the lungs. Herein, we …