Macrophage-osteoclast associations: origin, polarization, and subgroups
Y Sun, J Li, X Xie, F Gu, Z Sui, K Zhang… - Frontiers in …, 2021 - frontiersin.org
Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …
between bone remodeling and resorption, which is necessary for maintaining a normal bone …
The macrophage-osteoclast axis in osteoimmunity and osteo-related diseases
Y Yao, X Cai, F Ren, Y Ye, F Wang, C Zheng… - Frontiers in …, 2021 - frontiersin.org
Osteoimmunity is involved in regulating the balance of bone remodeling and resorption, and
is essential for maintaining normal bone morphology. The interaction between immune cells …
is essential for maintaining normal bone morphology. The interaction between immune cells …
Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
Y Zhou, D Yang, Q Yang, X Lv, W Huang… - Nature …, 2020 - nature.com
Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-
sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic …
sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic …
Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA
X Chen, Z Wan, L Yang, S Song, Z Fu, K Tang… - Journal of …, 2022 - Springer
Background Periodontitis is characterized by progressive inflammation and alveolar bone
loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like …
loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like …
Impact of the host response and osteoblast lineage cells on periodontal disease
M Zhou, DT Graves - Frontiers in immunology, 2022 - frontiersin.org
Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …
RNA-seq experiments have provided new insight into how resident cells and infiltrating …
Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration
Macrophage has been gradually recognized as a central regulator in tissue regeneration,
and the study of how macrophage mediates biomaterials-induced bone regeneration …
and the study of how macrophage mediates biomaterials-induced bone regeneration …
Dual-targeted nanodiscs revealing the cross-talk between osteogenic differentiation of mesenchymal stem cells and macrophages
L Chen, C Yu, W Xu, Y Xiong, P Cheng, Z Lin… - ACS …, 2023 - ACS Publications
Ongoing research has highlighted the significance of the cross-play of macrophages and
mesenchymal stem cells (MSCs). Lysine-specific demethylase 6B (KDM6B) has been …
mesenchymal stem cells (MSCs). Lysine-specific demethylase 6B (KDM6B) has been …
Chitosan derived nitrogen-doped carbon dots suppress osteoclastic osteolysis via downregulating ROS
R Chen, G Liu, X Sun, X Cao, W He, X Lin, Q Liu… - Nanoscale, 2020 - pubs.rsc.org
Osteoclasts are the main cells involved in normal bone remodeling and pathological bone
destruction in vivo. Overactivation of osteoclasts can lead to osteolytic diseases, including …
destruction in vivo. Overactivation of osteoclasts can lead to osteolytic diseases, including …
Improved Immunoregulation of Ultra-Low-Dose Silver Nanoparticle-Loaded TiO2 Nanotubes via M2 Macrophage Polarization by Regulating GLUT1 and Autophagy
Introduction The bone regeneration of endosseous implanted biomaterials is often impaired
by the host immune response, especially macrophage-related inflammation which plays an …
by the host immune response, especially macrophage-related inflammation which plays an …
Butyrate protects against MRSA pneumonia via regulating gut-lung microbiota and alveolar macrophage M2 polarization
Y Zhao, H Sun, Y Chen, Q Niu, Y Dong, M Li, Y Yuan… - Mbio, 2023 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) is a well-recognized cause of bacterial
pneumonia in general. The gut microbiota and their metabolic byproducts act as important …
pneumonia in general. The gut microbiota and their metabolic byproducts act as important …