Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …

Osteoimmunity is involved in regulating the balance of bone remodeling and resorption, and
is essential for maintaining normal bone morphology. The interaction between immune cells …

Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-
sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic …

Background Periodontitis is characterized by progressive inflammation and alveolar bone
loss resulting in tooth loss finally. Macrophages including pro-inflammatory M1-like …

Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …

Macrophage has been gradually recognized as a central regulator in tissue regeneration,
and the study of how macrophage mediates biomaterials-induced bone regeneration …

Ongoing research has highlighted the significance of the cross-play of macrophages and
mesenchymal stem cells (MSCs). Lysine-specific demethylase 6B (KDM6B) has been …

Osteoclasts are the main cells involved in normal bone remodeling and pathological bone
destruction in vivo. Overactivation of osteoclasts can lead to osteolytic diseases, including …

Introduction The bone regeneration of endosseous implanted biomaterials is often impaired
by the host immune response, especially macrophage-related inflammation which plays an …

Methicillin-resistant Staphylococcus aureus (MRSA) is a well-recognized cause of bacterial
pneumonia in general. The gut microbiota and their metabolic byproducts act as important …