Background Successful development of agents that improve cognition and behavior in
Alzheimer's disease (AD) is critical to improving the lives of patients manifesting the …

Adenosine exerts an important role in the modulation of central nervous system (CNS)
activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes …

The clinical and pathophysiological correlates of locus coeruleus (LC) degeneration in
Alzheimer's disease (AD) could be clarified using a method to index LC integrity in vivo …

Background Subjective cognitive decline (SCD) and anxiety symptoms both predict
neurocognitive disorders, but the two correlate strongly with each other. It is unclear whether …

Summary Alzheimer's disease (AD), which accounts for most of the dementia cases, is,
aside from cognitive deterioration, often characterized by the presence of non-cognitive …

Introduction: Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) are associated
with significant negative outcomes for patients and their caregivers. Agitation, one of the …

The Syzygium cumini (L.) Skeels is reported to have medicinal properties, but its benefits on
age-related neurological changes have not been previously explored. In the current study …

Introduction Neuropsychiatric symptoms (NPS) in Alzheimer's Disease (AD) are associated
with negative outcomes for patients and their care partners. Agitation is a common and …

Objective To investigate the relationship between Alzheimer's disease biomarkers and
neuropsychiatric symptoms. Methods Data from two large cohort studies, the Dutch …

Even though the involvement of serotonin (5-hydroxytryptamine; 5-HT) and its receptors in
Alzheimer's disease (AD) is widely accepted, data on the expression and the role of 5-HT 7 …