Therapeutic potential of hesperidin and its aglycone hesperetin: Cell cycle regulation and apoptosis induction in cancer models

JMPF de Oliveira, C Santos, E Fernandes - Phytomedicine, 2020 - Elsevier
Background The ability of cancer cells to divide without restriction and to escape
programmed cell death is a feature of the proliferative state. Citrus flavanones are flavonoids …

Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia

IU Okagu, JC Ndefo, EC Aham… - Frontiers in …, 2021 - frontiersin.org
The health benefits and toxicity of plant products are largely dependent on their secondary
metabolite contents. These compounds are biosynthesized by plants as protection …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells

V Kuete, LP Sandjo, AT Mbaveng, JA Seukep… - … and Alternative Medicine, 2015 - Springer
Background Malignacies are still a major public concern worldwide and despite the
intensive search for new chemotherapeutic agents, treatment still remains a challenging …

Neuroprotective and acetylcholinesterase inhibitory activities of alkaloids from Solanum lyratum Thunb.: An in vitro and in silico analyses

Y Chang, M Bai, X Zhang, S Shen, JY Hou, GD Yao… - Phytochemistry, 2023 - Elsevier
The n-BuOH extract from the herb of Solanum lyratum Thunb.(Solanaceae) was purified by
various chromatographic methods, which led to the isolation of seven undescribed alkaloids …

Potential of African flora to combat tuberculosis and drug resistance of Mycobacteria: Rationale classification of antimycobacterial agents from a natural source

CF Tchinda, V Kuete - Advances in Botanical Research, 2023 - Elsevier
This chapter presents a synopsis of African medicinal plants and their derived products with
antimycobacterial properties. Several secondary plant metabolites are reported to have anti …

Exploring cancer therapeutics with natural products from African medicinal plants, part II: alkaloids, terpenoids and flavonoids

JN Nwodo, A Ibezim, CV Simoben… - Anti-Cancer Agents in …, 2016 - ingentaconnect.com
Cancer stands as second most common cause of disease-related deaths in humans.
Resistance of cancer to chemotherapy remains challenging to both scientists and …

Alkamides: a critical reconsideration of a multifunctional class of unsaturated fatty acid amides

H Greger - Phytochemistry reviews, 2016 - Springer
Alkamides are natural products formed by connecting straight-chain, mostly unsaturated,
aliphatic acids with various amines by an amide linkage. More than 300 derivatives are …

Chemical Constituents of the Bark of Zanthoxylum gilletii (Rutaceae) and Their In Vitro Antiplasmodial and Molecular Docking Studies

LC Dzouemo, G Mouthé Happi, SA Ahmed… - Journal of …, 2022 - Wiley Online Library
The phytochemical investigations of the methanol extract of Zanthoxylum gilletii bark led to
the isolation of thirteen compounds identified as two alkaloids including one acridone 5 …

Antibacterial activities of Fagara macrophylla, Canarium schweinfurthii, Myrianthus arboreus, Dischistocalyx grandifolius and Tragia benthamii against multi-drug …

JA Seukep, B Ngadjui, V Kuete - Springerplus, 2015 - Springer
Bacterial infections caused by multidrug resistant phenotypes constitute a worldwide health
concern. The present study was designed to evaluate the in vitro antibacterial activities of …