[HTML][HTML] Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Microneedles as a momentous platform for psoriasis therapy and diagnosis: A state-of-the-art review

BHJ Gowda, MG Ahmed, U Hani, P Kesharwani… - International Journal of …, 2023 - Elsevier
Psoriasis is a chronic, autoimmune, and non-communicable skin disease with a worldwide
prevalence rate of 2–3%, creating an economic burden on global health. Some significant …

Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?

WA Verri Jr, TM Cunha, CA Parada, S Poole… - Pharmacology & …, 2006 - Elsevier
Pain is one of the classical signs of the inflammatory process in which sensitization of the
nociceptors is the common denominator. This sensitization causes hyperalgesia or allodynia …

Formatted anti–tumor necrosis factor α VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen …

K Coppieters, T Dreier, K Silence… - Arthritis & …, 2006 - Wiley Online Library
Objective The advent of tumor necrosis factor (TNF)–blocking drugs has provided
rheumatologists with an effective, but highly expensive, treatment for the management of …

[HTML][HTML] New insights in the immunologic basis of psoriasis

KE Nograles, B Davidovici… - Seminars in cutaneous …, 2010 - ncbi.nlm.nih.gov
Psoriasis vulgaris is a multi-factorial heritable disease characterized by severe inflammation
resulting in poorly differentiated, hyperproliferative keratinocytes. Recent advances in …

Cancer recurrence following immune-suppressive therapies in patients with immune-mediated diseases: a systematic review and meta-analysis

E Shelton, D Laharie, FI Scott, R Mamtani, JD Lewis… - Gastroenterology, 2016 - Elsevier
Background & Aims Physicians frequently encounter patients with immune-mediated
diseases and a history of malignancy. There are limited data on the safety of …

Tumor necrosis factor-α inhibitor-induced psoriasis or psoriasiform exanthemata: first 120 cases from the literature including a series of six new patients

U Wollina, G Hansel, A Koch, J Schönlebe… - American journal of …, 2008 - Springer
Tumor necrosis factor-α (TNFα) inhibition is effective in the treatment of moderate-to-severe
psoriasis. We report on 120 patients from the literature including six new patients (three …

Efficacy of tumour necrosis factor blockers in reducing uveitis flares in patients with spondylarthropathy: a retrospective study

S Guignard, L Gossec, C Salliot… - Annals of the …, 2006 - ard.bmj.com
Objective: To evaluate the efficacy of anti-tumour necrosis factor (TNF) treatments (given for
rheumatological manifestations) in reducing uveitis flares in patients with …

[HTML][HTML] Impact of TNF-α inhibitors on body weight and BMI: a systematic review and meta-analysis

O Patsalos, B Dalton, J Leppanen… - Frontiers in …, 2020 - frontiersin.org
Objective The aim of this systematic review and meta-analysis of longitudinal studies was to
ascertain to effects of TNF-α inhibitor therapy on body weight and BMI. Methods Three …

Distinct modes of TNF signaling through its two receptors in health and disease

KSN Atretkhany, VS Gogoleva… - Journal of leukocyte …, 2020 - academic.oup.com
TNF is a key proinflammatory and immunoregulatory cytokine whose deregulation is
associated with the development of autoimmune diseases and other pathologies. Recent …