Technical challenges of studying early human development

PJ Rugg-Gunn, N Moris, PPL Tam - Development, 2023 - journals.biologists.com
Recent years have seen exciting progress across human embryo research, including new
methods for culturing embryos, transcriptional profiling of embryogenesis and gastrulation …

Human embryo models made from pluripotent stem cells are not synthetic; they aren't embryos, either

HL Landecker, AT Clark - Cell stem cell, 2023 - cell.com
Embryo models are potentially highly impactful for human health research because their
development recapitulates otherwise inaccessible events in a poorly understood area of …

Navigating parent–child disagreement about fertility preservation in minors: scoping review and ethical considerations

M Bayefsky, D Vieira, A Caplan… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND Offering fertility preservation (FP) prior to gonadotoxic therapy, including
cancer care and gender-affirming treatment, is now considered standard of care …

Survey of 243 ART patients having made a final disposition decision about their surplus cryopreserved embryos: the crucial role of symbolic embryo representation

C Bruno, C Dudkiewicz-Sibony, I Berthaut… - Human …, 2016 - academic.oup.com
STUDY QUESTION In couples who have chosen and confirmed the fate of surplus frozen
embryos, which factors influence their decision, with a special emphasis on their symbolic …

[HTML][HTML] In-vitro metaphors: ART beneficiaries' meaning-making about human embryos in the context of IVF in Portugal

C Delaunay, MJDS Santos, L Gouveia - Reproductive Biomedicine & …, 2021 - Elsevier
This article proposes a metaphorical approach to the meaning-making of Portuguese
assisted reproductive technology (ART) beneficiaries about human embryos created in vitro …

An alternative proposal to the destruction of abandoned human embryos

N Gleicher, AL Caplan - Nature Biotechnology, 2018 - nature.com
To the Editor: Since the world's first in vitro fertilization (IVF) birth in 1978, over 6 million
healthy offspring have been born through IVF—an accomplishment that was celebrated with …

[HTML][HTML] Attitudes and values among the Swedish general public to using human embryonic stem cells for medical treatment

Å Grauman, M Hansson, D Nyholm, E Jiltsova… - BMC Medical …, 2022 - Springer
Background The use of human embryonic stem cells (ES cells) for the development of
medical therapies is surrounded with moral concerns. The aim of this study was to assess …

Gamete and embryo donation for research: what might shape the willingness to donate among gamete donors and recipients?

S Pinto da Silva, C de Freitas, M Severo… - Journal of assisted …, 2022 - Springer
Purpose Research using gametes and embryos donated by reproductive and third-party
donors contributed to substantial, albeit contentious achievements. The views of gamete …

Factors associated with willingness to donate embryos for research among couples undergoing IVF

C Samorinha, M Severo, E Alves, H Machado… - Reproductive …, 2016 - Elsevier
Abstract Between 2011 and 2012, 213 heterosexual couples undergoing fertility treatments
in a Portuguese public fertility centre were systematically recruited to assess factors …

Ethical and moral perspectives of individuals who considered/used preimplantation (embryo) genetic testing

J Zhang, LM Pastore, M Sarwana… - Journal of Genetic …, 2022 - Wiley Online Library
This study examined perspectives on the ethical implications of preimplantation genetic
testing (PGT) among individuals who actually (not hypothetically) used or considered using …