Synthetic chlorins, possible surrogates for chlorophylls, prepared by derivatization of porphyrins

M Taniguchi, JS Lindsey - Chemical reviews, 2017 - ACS Publications
Chlorophylls make Earth green, are the central constituents in the engine of photosynthesis,
and not surprisingly have garnered immense attention. A chlorin, the core chromophore of a …

Photosensitized singlet oxygen and its applications

MC DeRosa, RJ Crutchley - Coordination chemistry reviews, 2002 - Elsevier
The study of singlet molecular oxygen production and reactivity has emerged as a rich and
diverse area with implications in fields ranging from polymer science to cancer therapy. In …

Conjugated photosensitizers for imaging and PDT in cancer research

JCS Simões, S Sarpaki… - Journal of medicinal …, 2020 - ACS Publications
Early cancer detection and perfect understanding of the disease are imperative toward
efficient treatments. It is straightforward that, for choosing a specific cancer treatment …

Oxygen-generating hybrid nanoparticles to enhance fluorescent/photoacoustic/ultrasound imaging guided tumor photodynamic therapy

S Gao, G Wang, Z Qin, X Wang, G Zhao, Q Ma, L Zhu - Biomaterials, 2017 - Elsevier
Photodynamic therapy (PDT) is a promising tumor treatment modality that can convert
oxygen into cytotoxic singlet oxygen (SO) via photosensitizer to ablate tumor growth …

Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia

H Ding, H Yu, Y Dong, R Tian, G Huang… - Journal of Controlled …, 2011 - Elsevier
Photodynamic therapy (PDT) is an emerging clinical modality for the treatment of a variety of
diseases. Most photosensitizers are hydrophobic and poorly soluble in water. Many new …

Porphyrins in photodynamic therapy-a search for ideal photosensitizers

SK Pushpan, S Venkatraman, VG Anand… - … -Anti-Cancer Agents, 2002 - ingentaconnect.com
The utility of light as a therapeutic agent can be traced back over thousands of years when it
was used in Ancient Egypt, India and China to treat a variety of skin diseases like psoriasis …

Overcoming the challenges of infrared photosensitizers in photodynamic therapy: The making of redaporfin

LG Arnaut, MM Pereira - Chemical Communications, 2023 - pubs.rsc.org
We offer a personal account of the discovery and development of a photosensitizer for
photodynamic therapy (PDT) of cancer, from bench to bedside. We emphasize the more …

Antimicrobial photodynamic treatment (aPDT) as an innovative technology to control spoilage and pathogenic microorganisms in agri-food products: An updated …

L do Prado-Silva, GTP Brancini, GÚL Braga, X Liao… - Food Control, 2022 - Elsevier
Antimicrobial photodynamic treatment (aPDT) is a light-based method developed for the
inactivation of microorganisms. With the emergence of antifungal-and antibiotic-resistant …

Photodynamic inactivation of bacteria with porphyrin derivatives: effect of charge, lipophilicity, ROS generation, and cellular uptake on their biological activity in vitro

A Sułek, B Pucelik, M Kobielusz, A Barzowska… - International Journal of …, 2020 - mdpi.com
Resistance of microorganisms to antibiotics has led to research on various therapeutic
strategies with different mechanisms of action, including photodynamic inactivation (PDI). In …

[HTML][HTML] Photodynamic therapy: A special emphasis on nanocarrier-mediated delivery of photosensitizers in antimicrobial therapy

C Garapati, SHS Boddu, S Jacob, KM Ranch… - Arabian Journal of …, 2023 - Elsevier
Resistance to antimicrobial drugs is an impending healthcare problem of growing
significance. In the post-antibiotic era, there is a huge push to develop new tools for …