Resistance to anti-VEGF therapy in neovascular age-related macular degeneration: a comprehensive review

S Yang, J Zhao, X Sun - Drug design, development and therapy, 2016 - Taylor & Francis
As a progressive chronic disease, age-related macular degeneration (AMD) is the leading
cause of irreversible vision impairment worldwide. Experimental and clinical evidence has …

Retinal angiomatous proliferation

ASH Tsai, N Cheung, ATL Gan, GJ Jaffe… - Survey of …, 2017 - Elsevier
Retinal angiomatous proliferation (RAP) is a unique variant of neovascular age-related
macular degeneration. Published studies have estimated that up to 15% of patients with …

Type 3 neovascularization: evolution, association with pigment epithelial detachment, and treatment response as revealed by spectral domain optical coherence …

A Nagiel, D Sarraf, SR Sadda, RF Spaide, JJ Jung… - Retina, 2015 - journals.lww.com
Purpose: To demonstrate the evolution and treatment response of Type 3
neovascularization using spectral domain optical coherence tomography. Methods: We …

Outcomes in eyes with retinal angiomatous proliferation in the comparison of age-related macular degeneration treatments trials (CATT)

E Daniel, J Shaffer, G Ying, JE Grunwald, DF Martin… - Ophthalmology, 2016 - Elsevier
Purpose To compare baseline characteristics, visual acuity (VA), and morphologic outcomes
between eyes with retinal angiomatous proliferation (RAP) and all other eyes among …

Neurofibromatosis: an update of ophthalmic characteristics and applications of optical coherence tomography

B Abdolrahimzadeh, DC Piraino, G Albanese… - Clinical …, 2016 - Taylor & Francis
Neurofibromatosis (NF) is a multisystem disorder and tumor predisposition syndrome
caused by genetic mutation on chromosome 17-17q11. 2 in NF type 1 (NF1), and on …

Treating the untreatable patient: current options for the management of treatment‐resistant neovascular age‐related macular degeneration

GK Broadhead, T Hong, AA Chang - Acta ophthalmologica, 2014 - Wiley Online Library
Anti‐vascular endothelial growth factor (anti‐VEGF) agents represent the current standard of
care for neovascular age‐related macular degeneration (nAMD). Although effective in a …

How has high-resolution multimodal imaging refined our understanding of the vasogenic process in type 3 neovascularization?

G Querques, EH Souied, KB Freund - Retina, 2015 - journals.lww.com
J. Donald M. Gass defined a terminology for neovascularization in macular diseases that is
based on the anatomical location of the neovessels. He proposed the term “Type 1 …

An update on the ophthalmologic features in the phakomatoses

S Abdolrahimzadeh, AM Plateroti… - Journal of …, 2016 - Wiley Online Library
Neurofibromatosis type 1, tuberous sclerosis complex, and Von Hippel‐Lindau disease,
historically classified as the phakomatoses, are hereditary multisystem disorders …

Clinical pathological features and current animal models of type 3 macular neovascularization

W Qiang, R Wei, Y Chen, D Chen - Frontiers in Neuroscience, 2021 - frontiersin.org
Type 3 macular neovascularization (MNV3), or retinal angiomatous proliferation (RAP), is a
distinct type of neovascular age-related macular degeneration (AMD), which is a leading …

[HTML][HTML] Retinal microglia are critical for subretinal neovascular formation

A Usui-Ouchi, Y Usui, T Kurihara, E Aguilar, MI Dorrell… - JCI insight, 2020 - ncbi.nlm.nih.gov
Abnormal subretinal neovascularization is a characteristic of vision-threatening retinal
diseases, including macular telangiectasia (MacTel) and retinal angiomatous proliferation …