A perspective on brain-age estimation and its clinical promise

C Gaser, P Kalc, JH Cole - Nature computational science, 2024 - nature.com
Brain-age estimation has gained increased attention in the neuroscientific community owing
to its potential use as a biomarker of brain health. The difference between estimated and …

Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages

RP Dörfel, JM Arenas‐Gomez, PM Fisher… - Human Brain …, 2023 - Wiley Online Library
Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to
assess the biological age of the human brain. The difference between a person's …

[HTML][HTML] Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease

PR Millar, BA Gordon, JK Wisch, SA Schultz… - Molecular …, 2023 - Springer
Background “Brain-predicted age” estimates biological age from complex, nonlinear
features in neuroimaging scans. The brain age gap (BAG) between predicted and …

Explainable brain age prediction using covariance neural networks

S Sihag, G Mateos, C McMillan… - Advances in Neural …, 2024 - proceedings.neurips.cc
In computational neuroscience, there has been an increased interest in developing machine
learning algorithms that leverage brain imaging data to provide estimates of" brain age" for …

Mapping the neurodevelopmental predictors of psychopathology

RJ Jirsaraie, MM Gatavins, AR Pines, S Kandala… - Molecular …, 2024 - nature.com
Neuroimaging research has uncovered a multitude of neural abnormalities associated with
psychopathology, but few prediction-based studies have been conducted during …

[HTML][HTML] Brain age has limited utility as a biomarker for capturing fluid cognition in older individuals

A Tetereva, N Pat - Elife, 2024 - elifesciences.org
One well-known biomarker candidate that supposedly helps capture fluid cognition is Brain
Age, or a predicted value based on machine-learning models built to predict chronological …

Transferability of Covariance Neural Networks

S Sihag, G Mateos, C McMillan… - IEEE Journal of Selected …, 2024 - ieeexplore.ieee.org
Graph convolutional networks (GCN) leverage topology-driven graph convolutional
operations to combine information across the graph for inference tasks. In our recent work …

BrainAGE: Revisited and reframed machine learning workflow

P Kalc, R Dahnke, F Hoffstaedter, C Gaser… - 2024 - Wiley Online Library
Since the introduction of the BrainAGE method, novel machine learning methods for brain
age prediction have continued to emerge. The idea of estimating the chronological age from …

[HTML][HTML] “Puberty age gap”: new method of assessing pubertal timing and its association with mental health problems

N Dehestani, N Vijayakumar, G Ball, S Mansour L… - Molecular …, 2024 - nature.com
Puberty is linked to mental health problems during adolescence, and in particular, the timing
of puberty is thought to be an important risk factor. This study developed a new measure of …

[HTML][HTML] Examining the reliability of brain age algorithms under varying degrees of participant motion

JL Hanson, DJ Adkins, E Bacas, P Zhou - Brain Informatics, 2024 - Springer
Brain age algorithms using data science and machine learning techniques show promise as
biomarkers for neurodegenerative disorders and aging. However, head motion during MRI …