The role of AMPK in cancer metabolism and its impact on the immunomodulation of the tumor microenvironment
CK Keerthana, TP Rayginia, SC Shifana… - Frontiers in …, 2023 - frontiersin.org
Adenosine monophosphate-activated protein kinase (AMPK) is a key metabolic sensor that
is pivotal for the maintenance of cellular energy homeostasis. AMPK contributes to diverse …
is pivotal for the maintenance of cellular energy homeostasis. AMPK contributes to diverse …
Metabolic reprogramming in glioma
M Strickland, EA Stoll - Frontiers in cell and developmental biology, 2017 - frontiersin.org
Many cancers have long been thought to primarily metabolize glucose for energy production—
a phenomenon known as the Warburg Effect, after the classic studies of Otto Warburg in the …
a phenomenon known as the Warburg Effect, after the classic studies of Otto Warburg in the …
[HTML][HTML] Acetyl-CoA carboxylase 1-dependent protein acetylation controls breast cancer metastasis and recurrence
MR Garcia, B Steinbauer, K Srivastava, M Singhal… - Cell metabolism, 2017 - cell.com
Breast tumor recurrence and metastasis represent the main causes of cancer-related death
in women, and treatments are still lacking. Here, we define the lipogenic enzyme acetyl-CoA …
in women, and treatments are still lacking. Here, we define the lipogenic enzyme acetyl-CoA …
The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator
The AMP-activated protein kinase (AMPK) is a central regulator of cellular metabolism and
energy homeostasis in mammalian tissues. Pertinent to cancer biology is the fact that AMPK …
energy homeostasis in mammalian tissues. Pertinent to cancer biology is the fact that AMPK …
[HTML][HTML] Targeting AMPK for cancer prevention and treatment
AMP-activated protein kinase (AMPK) is an important mediator in maintaining cellular
energy homeostasis. AMPK is activated in response to a shortage of energy. Once activated …
energy homeostasis. AMPK is activated in response to a shortage of energy. Once activated …
The AMPK inhibitor compound C is a potent AMPK-independent antiglioma agent
AMP-activated protein kinase (AMPK) is an evolutionarily conserved energy sensor
important for cell growth, proliferation, survival, and metabolic regulation. Active AMPK …
important for cell growth, proliferation, survival, and metabolic regulation. Active AMPK …
Dissecting the dual role of AMPK in cancer: from experimental to human studies
G Zadra, JL Batista, M Loda - Molecular cancer research, 2015 - AACR
The precise role of 5′ AMP-activated kinase (AMPK) in cancer and its potential as a
therapeutic target is controversial. Although it is well established that activation of this …
therapeutic target is controversial. Although it is well established that activation of this …
AMPK: a contextual oncogene or tumor suppressor?
J Liang, GB Mills - Cancer research, 2013 - AACR
The AMP-activated protein kinase (AMPK) functions to monitor and maintain energy
homeostasis at the cellular and organism level. AMPK was perceived historically primarily …
homeostasis at the cellular and organism level. AMPK was perceived historically primarily …
Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
X Liu, RR Chhipa, S Pooya… - Proceedings of the …, 2014 - National Acad Sciences
The multifunctional AMPK-activated protein kinase (AMPK) is an evolutionarily conserved
energy sensor that plays an important role in cell proliferation, growth, and survival. It …
energy sensor that plays an important role in cell proliferation, growth, and survival. It …
Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer
Theranostic agents should ideally be renally cleared and biodegradable. Here, we report
the synthesis, characterization and theranostic applications of fluorescent ultrasmall gold …
the synthesis, characterization and theranostic applications of fluorescent ultrasmall gold …