Castleman disease (CD), a heterogeneous group of disorders that share morphological
features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical …

Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

Opposing effects of inflammation on cancer have been described. Acute inflammation
usually counteracts cancer development, while chronic inflammation promotes cancer …

Abstract Interleukin-6 (IL-6) has received particular attention in the pathogenesis of cervical
cancer, although the underlying mechanism remains elusive. This study revealed that IL-6 …

Viruses have evolved elegant mechanisms to evade detection and destruction by the host
immune system. One of the evasion strategies that have been adopted by large DNA viruses …

It is estimated that viral infections contribute to 15–20% of all human cancers. As obligatory
intracellular parasites, viruses encode proteins that reprogram host cellular signaling …

Abstract Interleukin‐6 (IL‐6) is a multifunctional cytokine produced by macrophages, T cells,
B cells, endothelial cells and tumour cells. Interleukin‐6 is able to promote tumour growth by …

Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with three malignancies—
Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's …