Degradable biomedical elastomers: paving the future of tissue repair and regenerative medicine

B Jia, H Huang, Z Dong, X Ren, Y Lu… - Chemical Society …, 2024 - pubs.rsc.org
Degradable biomedical elastomers (DBE), characterized by controlled biodegradability,
excellent biocompatibility, tailored elasticity, and favorable network design and …

[HTML][HTML] 3D bioprinting in cardiac tissue engineering

Z Wang, L Wang, T Li, S Liu, B Guo, W Huang, Y Wu - Theranostics, 2021 - ncbi.nlm.nih.gov
Heart disease is the main cause of death worldwide. Because death of the myocardium is
irreversible, it remains a significant clinical challenge to rescue myocardial deficiency …

Poly (glycerol sebacate) in biomedical applications—A review of the recent literature

L Vogt, F Ruther, S Salehi… - Advanced healthcare …, 2021 - Wiley Online Library
Abstract Poly (glycerol sebacate)(PGS) continues to attract attention for biomedical
applications owing to its favorable combination of properties. Conventionally polymerized by …

Biodegradable elastomers for biomedical applications

S Chen, Y Wang, L Yang, C Chu, S Cao, Z Wang… - Progress in Polymer …, 2023 - Elsevier
Synthetic biodegradable elastomers, such as polyesters and polyurethanes have
revolutionized biomedical therapeutic strategies and devices. Driven by innovations in …

[HTML][HTML] An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction

L Zhang, Z Bei, T Li, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …

A perfusable, multifunctional epicardial device improves cardiac function and tissue repair

S Huang, D Lei, Q Yang, Y Yang, C Jiang, H Shi… - Nature medicine, 2021 - nature.com
Despite advances in technologies for cardiac repair after myocardial infarction (MI), new
integrated therapeutic approaches still need to be developed. In this study, we designed a …

Mussel patterned with 4D biodegrading elastomer durably recruits regenerative macrophages to promote regeneration of craniofacial bone

X Liu, W Chen, B Shao, X Zhang, Y Wang, S Zhang… - Biomaterials, 2021 - Elsevier
Crosstalk between bone marrow mesenchymal stem cells (BMSCs) and macrophages plays
vital role in bone healing. By investigating the mechanism of collagen membrane-guided …

ROS-responsive polyurethane fibrous patches loaded with methylprednisolone (MP) for restoring structures and functions of infarcted myocardium in vivo

Y Yao, J Ding, Z Wang, H Zhang, J Xie, Y Wang… - Biomaterials, 2020 - Elsevier
Reactive oxygen species (ROS) play an important role in the pathogenesis of numerous
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …

Chitosan hydrogel as tissue engineering scaffolds for vascular regeneration applications

Q Wang, X Wang, Y Feng - Gels, 2023 - mdpi.com
Chitosan hydrogels have a wide range of applications in tissue engineering scaffolds,
mainly due to the advantages of their chemical and physical properties. This review focuses …

Microneedle-mediated gene delivery for the treatment of ischemic myocardial disease

H Shi, T Xue, Y Yang, C Jiang, S Huang, Q Yang… - Science …, 2020 - science.org
Cardiovascular disorders are still the primary cause of mortality worldwide. Although
intramyocardial injection can effectively deliver agents to the myocardium, this approach is …