Analysis of racial/ethnic representation in select basic and applied cancer research studies

S Guerrero, A López-Cortés, A Indacochea… - Scientific reports, 2018 - nature.com
Over the past decades, consistent studies have shown that race/ethnicity have a great
impact on cancer incidence, survival, drug response, molecular pathways and epigenetics …

Function of microRNA-124 in the Pathogenesis of Cancer

Y Liu, Y Yang, X Wang, S Yin… - International …, 2023 - spandidos-publications.com
Non-coding RNAs with a length of 22-24 nt are known as microRNAs (miRNAs or miRs),
which are critical regulators of protein translation. Over the past 10 years, the roles of …

Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer

A López-Cortés, C Paz-y-Miño, S Guerrero… - The …, 2020 - nature.com
Colorectal cancer is one of the leading causes of cancer death worldwide. Over the last
decades, several studies have shown that tumor-related genomic alterations predict tumor …

An updated examination of the perception of barriers for pharmacogenomics implementation and the usefulness of drug/gene pairs in Latin America and the …

A Salas-Hernández, M Galleguillos… - Frontiers in …, 2023 - frontiersin.org
Pharmacogenomics (PGx) is considered an emergent field in developing countries.
Research on PGx in the Latin American and the Caribbean (LAC) region remains scarce …

Salivary microRNAs for early detection of head and neck squamous cell carcinoma: A case‐control study in the high altitude mestizo ecuadorian population

C Salazar-Ruales, JV Arguello… - BioMed research …, 2018 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with
the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring …

OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine

A López-Cortés, C Paz-y-Miño, S Guerrero… - Scientific reports, 2020 - nature.com
Breast cancer (BC) is the leading cause of cancer-related death among women and the
most commonly diagnosed cancer worldwide. Although in recent years large-scale efforts …

Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis

A López-Cortés, C Paz-y-Miño, A Cabrera-Andrade… - Scientific reports, 2018 - nature.com
Consensus strategy was proved to be highly efficient in the recognition of gene-disease
association. Therefore, the main objective of this study was to apply theoretical approaches …

Prediction of breast cancer proteins involved in immunotherapy, metastasis, and RNA-binding using molecular descriptors and artificial neural networks

A López-Cortés, A Cabrera-Andrade… - Scientific reports, 2020 - nature.com
Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein
expression deregulation, signaling pathway alterations, hormone disruption, ethnicity and …

Mutational analysis of oncogenic AKT1 gene associated with breast cancer risk in the high altitude ecuadorian mestizo population

A López-Cortés, PE Leone… - BioMed Research …, 2018 - Wiley Online Library
Breast cancer is the leading cause of cancer‐related death among women worldwide. AKT1
encodes the kinase B alpha protein. The rs121434592, rs12881616, rs11555432 …

The close interaction between hypoxia-related proteins and metastasis in pancarcinomas

A López-Cortés, L Prathap, E Ortiz-Prado… - Scientific Reports, 2022 - nature.com
Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access
to nutrients due to poor vascularization in the tissue, phenomenon known as hypoxia …