Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …

Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Biofilms are a complex group of microbial cells that adhere to the exopolysaccharide matrix
present on the surface of medical devices. Biofilm-associated infections in the medical …

The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-
existence between microorganisms and the host immune system in the endometrium. A …

Bacterial biofilms, which consist of three-dimensional extracellular polymeric substance
(EPS), not only function as signaling networks, provide nutritional support, and facilitate …

Chronic infections are frequently caused by polymicrobial biofilms. Importantly, these
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …

Biofilm formation is often considered the underlying reason why treatment with an
antimicrobial agent fails and as an estimated 65–80% of all human infections is thought to …

Unequivocal direct observations have established that the bacteria that cause device-
related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and …