Major depression represents a complex and prevalent psychological disease that is
characterized by persistent depressed mood, impaired cognitive function and complicated …

The neurotrophin hypothesis indicates that neurotrophic factors are important for the
pathophysiology of major depressive disorder (MDD), with alterations in peripheral …

Bipolar disorder is one of the severe mental diseases. Its high misdiagnosis rate and long-
time delayed diagnosis are related to the fact that the diagnosis procedure is mainly …

Although results are still preliminary, ketamine and classical hallucinogens have shown
promise in recent years as novel, fast-acting antidepressants, especially for the treatment of …

Several studies have shown that electroconvulsive therapy (ECT) results in increased
hippocampal volume. It is likely that a multitude of mechanisms including neurogenesis …

Aim Vascular endothelial growth factor (VEGF) has been implicated in mediating the effect of
antidepressant therapies as it plays a significant role in the neurogenesis. Anhedonia, an …

Electroconvulsive therapy (ECT) is a long-standing treatment choice for disorders such as
depression when pharmacological treatments have failed. However, a major drawback of …

Immunomodulation is increasingly being recognised as a part of mental diseases. Here, we
examined whether levels of immunological protein markers changed with depression, age …

Background Several lines of evidence are pointing towards an involvement of the vascular
endothelial growth factor (VEGF) in the pathophysiology of depression. There are studies …

Background Vascular endothelial growth factor (VEGF) is a candidate mediator of blood-
brain barrier (BBB) disruption in depression. However, previous studies have mainly …