[HTML][HTML] Recent advances in boronic acid-based optical chemosensors

X Wu, XX Chen, YB Jiang - Analyst, 2017 - pubs.rsc.org
Reversible covalent binding of boronic acids with polyols and Lewis bases has facilitated
the development of robust chemosensors for many biologically important species under …

Arylboronic acids and their myriad of applications beyond organic synthesis

NJ Hiller, NA do Amaral e Silva… - European Journal of …, 2020 - Wiley Online Library
Boron organometallic compounds are mainly known for their great value in organic
synthesis to construct biaryls in Suzuki couplings, for arylations of olefins, for C–S, C–O, and …

Optical analysis of reaction yield and enantiomeric excess: a new paradigm ready for prime time

BT Herrera, SL Pilicer, EV Anslyn… - Journal of the …, 2018 - ACS Publications
This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …

Molecular Recognition and Chirality Sensing of Epoxides in Water Using Endo-Functionalized Molecular Tubes

LL Wang, Z Chen, WE Liu, H Ke… - Journal of the …, 2017 - ACS Publications
Chiral epoxides are important intermediates in chemistry and biology. The high-throughput
screening of asymmetric epoxidation conditions requires fast determination of the absolute …

Quantitative chiroptical sensing of free amino acids, biothiols, amines, and amino alcohols with an aryl fluoride probe

FY Thanzeel, A Sripada, C Wolf - Journal of the American …, 2019 - ACS Publications
The comprehensive determination of the absolute configuration, enantiomeric ratio, and total
amount of standard amino acids by optical methods adaptable to high-throughput screening …

Enantioselective recognition of neutral molecules in water by a pair of chiral biomimetic macrocyclic receptors

H Chai, Z Chen, SH Wang, M Quan, LP Yang… - CCS …, 2020 - chinesechemsoc.org
Enantioselective recognition in water remains an ongoing challenge in supramolecular
chemistry but is routine in nature. Herein, we report the first enantiopure pair of biomimetic …

Unified sensing of the concentration and enantiomeric composition of chiral compounds with an achiral probe

A Sripada, FY Thanzeel, C Wolf - Chem, 2022 - cell.com
Long-standing impracticalities with optical chiral compound sensing have limited the
potential and acceptance of high-throughput experimentation technology despite the …

Concentration-Independent Stereodynamic g-Probe for Chiroptical Enantiomeric Excess Determination

P Zardi, K Wurst, G Licini, C Zonta - Journal of the American …, 2017 - ACS Publications
Enantiomeric excess (ee) determination is crucial in many aspects of science, from synthesis
to materials. Within this subject, coupling molecular sensors with chiroptical techniques is a …

A real-time strategy for chiroptical sensing and enantiomeric excess determination of primary amines via an acid–base reaction

D Wu, F Wang, C Ma, L Tan, W Cai, J Li, Y Kong - Organic letters, 2022 - ACS Publications
Two achiral aromatic carboxylic acids that included the 1, 8-naphthalimide group and an
imidazolium cation were synthesized and exploited as chiroptical sensors. These …

[HTML][HTML] High-throughput assay for determining enantiomeric excess of chiral diols, amino alcohols, and amines and for direct asymmetric reaction screening

EG Shcherbakova, TD James, P Anzenbacher Jr - Nature Protocols, 2020 - nature.com
Determining enantiomeric excess (ee) in chiral compounds is key to development of chiral
catalyst auxiliaries and chiral drugs. Here we describe a sensitive and robust fluorescence …