Advances in autophagy as a target in the treatment of tumours

Y Li, S Gao, X Du, J Ji, Y Xi, G Zhai - Journal of Drug Targeting, 2022 - Taylor & Francis
Autophagy is a multi-step lysosomal degradation process, which regulates energy and
material metabolism and has been used to maintain homeostasis. Autophagy has been …

Reduced DAPK1 expression promotes stem cell-like characteristics of prostate cancer cells by activating ZEB1 via Hippo/YAP signaling pathway

S Nong, Z Wei, Z Wang, L Ma, Y Guan… - Stem Cells and …, 2021 - liebertpub.com
Prostate cancer (PCa) is a malignant tumor that originates in the male genitourinary system.
Downregulation of death-associated protein kinase 1 (DAPK1) is closely related to PCa …

Clearing Properties Between Coconut Oil and Xylene in Histological Tissue Processing

OA Bright, DN Samuel, MA Adisa… - … of Histochemistry & …, 2024 - journals.sagepub.com
Xylene is the commonest clearing agent even though it is hazardous and costly. This study
evaluated the clearing properties of coconut oil as an alternative cost-effective clearing …

Dapk1 promoted inflammation of infantile pneumonia by p38MAPK/NF-κB signaling pathway

W Zhang - Molecular & Cellular Toxicology, 2021 - Springer
Background The present study was designed to investigate the function of death-associated
protein kinase 1 (DAPK1) in infantile pneumonia and explore the potential mechanism of the …

[HTML][HTML] Advancements in precision nanomedicine design targeting the anoikis-platelet interface of circulating tumor cells

M Tang, Z Zhang, P Wang, F Zhao, L Miao… - … Pharmaceutica Sinica B, 2024 - Elsevier
Tumor metastasis, the apex of cancer progression, poses a formidable challenge in
therapeutic endeavors. Circulating tumor cells (CTCs), resilient entities originating from …

Transfer Learning Based Approaches for Breast Cancer Classification using Mammogram Images

M Sharifujjaman, Z Ferdousee… - … on Computer and …, 2023 - ieeexplore.ieee.org
Breast cancer is a growing epidemic and a leading cause of death among women
worldwide. Mammographic imaging has been found to be highly effective in detecting breast …

[PDF][PDF] Antitumor potential of aqueous leaf extract of Leucocasia gigantea (Blume.) Schott in breast cancer metastasis

V Bindu, SN Deshpande, PSR Dwivedi… - Annals of …, 2023 - researchgate.net
One of the crucial components of cancer is metastasis, which spreads from the site of origin
to a different portion of the body. Prior studies on the plant have shown that the medicinal …

BRCA1 gene polymorphism and finger dermatoglyphic patterns in Ghanaian breast cancer patients: a quantitative cross-sectional approach

EO Nkansah, J Ahenkorah, K Adutwum-Ofosu… - Pan African Medical …, 2022 - ajol.info
Introduction: breast cancer development is linked to mutant single nucleotide polymorphism
of breast cancer type 1 (BRCA1) gene usually harboured within exon 11. It has also been …

[PDF][PDF] Anticancer effects of sanguinarine in triple-negative breast cancer cells via apoptosis induction and cell cycle arrest

SS Messeha, S Noel, NO Zarmouh, T Womble… - 2022 - academia.edu
Patients with triple-negative breast cancer (TNBC) are typically treated with non-targeted
chemotherapeutic agents, and the late disease stages are known to be resistant to …

Serum Lactate Dehydrogenase as a Potential Predictive Index of Chemotherapy Response in Breast Cancer Patients

GK Aryee, B Arko-Boham, NEB Antwi… - Health Sciences …, 2024 - journals.ug.edu.gh
Background: Monitoring treatment during breast cancer management is crucial. Lactate
dehydrogenase (LDH) expression and activity drive cancer progression through metabolic …