Radioactive main group and rare earth metals for imaging and therapy
TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …
medicine with great success for several decades. The majority of current clinical use …
Matching chelators to radiometals for radiopharmaceuticals
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …
properly harnessed, these have valuable emission properties that can be used for …
Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease
TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …
processes at the molecular and cellular levels in humans and other living systems …
A practical guide to the construction of radiometallated bioconjugates for positron emission tomography
Positron emission tomography (PET) has become a vital imaging modality in the diagnosis
and treatment of disease, most notably cancer. A wide array of small molecule PET …
and treatment of disease, most notably cancer. A wide array of small molecule PET …
The renaissance of the 68Ge/68Ga radionuclide generator initiates new developments in 68Ga radiopharmaceutical chemistry
F Roesch, PJ Riss - Current topics in medicinal chemistry, 2010 - ingentaconnect.com
68Ge/68Ga radionuclide generators have been investigated for almost fifty years now, since
the cyclotronindependent availability of positron emitting 68Ga via the 68Ge/68Ga system …
the cyclotronindependent availability of positron emitting 68Ga via the 68Ge/68Ga system …
Tailoring the Recognition Property of a 19F-Labeled Gallium-Based NMR Probe: The Influence of the Metal Center
J Liang, Z Xu, J Wu, Y Zhao - Analytical Chemistry, 2023 - ACS Publications
Chirality is a fundamental property of nature and an essential element of the life process. As
the biological activities, metabolic pathways, and toxicity of individual enantiomers are often …
the biological activities, metabolic pathways, and toxicity of individual enantiomers are often …
Modern developments in bifunctional chelator design for gallium radiopharmaceuticals
PRWJ Davey, BM Paterson - Molecules, 2022 - mdpi.com
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …
Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals
Over the past several decades, radionuclides have matured from largely esoteric and
experimental technologies to indispensible components of medical diagnostics. Driving this …
experimental technologies to indispensible components of medical diagnostics. Driving this …
Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions
V Carroll, DW Demoin, TJ Hoffman, SS Jurisson - Radiochimica acta, 2012 - degruyter.com
Radiometals play an important role in diagnostic and therapeutic radiopharmaceuticals. This
field of radiochemistry is multidisciplinary, involving radiometal production, separation of the …
field of radiochemistry is multidisciplinary, involving radiometal production, separation of the …
Bifunctional chelators in the design and application of radiopharmaceuticals for oncological diseases
D Sarko, M Eisenhut, U Haberkorn… - Current medicinal …, 2012 - ingentaconnect.com
Radiopharmaceuticals constitute diagnostic and therapeutic tools for both clinical and
preclinical applications. They are a blend of a tracer moiety that mediates a site specific …
preclinical applications. They are a blend of a tracer moiety that mediates a site specific …