New molecular entities and structure–activity relationships of drugs designed by the natural product derivatization method from 2010 to 2018
Q Cui, R Bian, F Xu, Q Li, W Wang, Q Bian - Studies in Natural Products …, 2021 - Elsevier
An important concept, the natural product derivatization method, was introduced and defined
to comprehensively evaluate the significance of natural product derivatization in the design …
to comprehensively evaluate the significance of natural product derivatization in the design …
[HTML][HTML] Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling
H Singhal, ME Greene, AL Zarnke, M Laine… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Major roadblocks to developing effective progesterone receptor (PR)-targeted therapies in
breast cancer include the lack of highly-specific PR modulators, a poor understanding of the …
breast cancer include the lack of highly-specific PR modulators, a poor understanding of the …
StackPR is a new computational approach for large-scale identification of progesterone receptor antagonists using the stacking strategy
N Schaduangrat, N Anuwongcharoen, MA Moni… - Scientific Reports, 2022 - nature.com
Progesterone receptors (PRs) are implicated in various cancers since their
presence/absence can determine clinical outcomes. The overstimulation of progesterone …
presence/absence can determine clinical outcomes. The overstimulation of progesterone …
3C. 3-Ketosteroid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
D Cain, J Cidlowski, DP Edwards, P Fuller… - IUPHAR/BPS guide to …, 2019 - journals.ed.ac.uk
Steroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on
Nuclear Hormone Receptors [65, 193]) are nuclear hormone receptors of the NR3 class …
Nuclear Hormone Receptors [65, 193]) are nuclear hormone receptors of the NR3 class …
3C. 3-Ketosteroid receptors in GtoPdb v. 2023.1
D Cain, J Cidlowski, DP Edwards, P Fuller… - IUPHAR/BPS Guide …, 2023 - journals.ed.ac.uk
Steroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on
Nuclear Hormone Receptors [75, 218, 3]) are nuclear hormone receptors of the NR3 class …
Nuclear Hormone Receptors [75, 218, 3]) are nuclear hormone receptors of the NR3 class …
Effects of Combination of Estradiol with Selective Progesterone Receptor Modulators (SPRMs) on Human Breast Cancer Cells In Vitro and In Vivo
Use of estrogen or estrogen/progestin combination was an approved regimen for
menopausal hormonal therapy (MHT). However, more recent patient-centered studies …
menopausal hormonal therapy (MHT). However, more recent patient-centered studies …
3C. 3-Ketosteroid receptors in GtoPdb v. 2021.3
D Cain, J Cidlowski, DP Edwards, P Fuller… - IUPHAR/BPS Guide …, 2021 - journals.ed.ac.uk
Steroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on
Nuclear Hormone Receptors [74, 215, 3]) are nuclear hormone receptors of the NR3 class …
Nuclear Hormone Receptors [74, 215, 3]) are nuclear hormone receptors of the NR3 class …
[图书][B] The Role of Metalloid/Metal Anions in Progesterone-Independent Activation of Progesterone Receptor
RM Gahtani - 2021 - search.proquest.com
Progesterone and progesterone receptor play a central role in hormone responsive tissue.
Although there is increasing evidence that disruption of the progesterone pathway is …
Although there is increasing evidence that disruption of the progesterone pathway is …
Model for Hormonal Emergency Contraception (HEC) in cycling and mated guinea pigs–Studies with the Progesterone Receptor Modulators (PRM) Ulipristal Acetate …
W Elger, B Schneider, Z Killeen, K Jewgenow… - The Journal of Steroid …, 2018 - Elsevier
A guinea pig model for new HEC methods is proposed. Two targets for HEC (Hormonal
Emergency Contraception), ovulation and conception (post-mating study), were investigated …
Emergency Contraception), ovulation and conception (post-mating study), were investigated …
[图书][B] Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors inform breast cancer prognosis and therapies
H Singhal - 2016 - search.proquest.com
Estrogen receptor alpha (ER) and progesterone receptor (PR) play critical roles in breast
cancer, however the clinical value of PR is controversial and it is unclear how PR modulates …
cancer, however the clinical value of PR is controversial and it is unclear how PR modulates …