The emergence of induced pluripotent stem cell (iPSC) technology paves the way to
generate large numbers of patient-specific endothelial cells (ECs) that can be potentially …

Cardiovascular disease (CVD) comprises a range of major clinical cardiac and circulatory
diseases, which produce immense health and economic burdens worldwide. Currently …

Aging is the biological process of declining physiologic function associated with increasing
mortality rate during advancing age. Humans and higher nonhuman primates exhibit …

The treatment of full thickness skin loss, which can be extensive in the case of large burns,
continues to represent a challenging clinical entity. This is due to an on‐going inability to …

Compromised alveolar development and pulmonary vascular remodeling are hallmarks of
pediatric lung diseases such as bronchopulmonary dysplasia (BPD) and alveolar capillary …

Rationale: Bone marrow (BM) cell therapy for ischemic heart disease (IHD) has shown
mixed results. Before the full potency of BM cell therapy can be realized, it is essential to …

For over a decade various cell populations have been investigated for their vasoreparative
potential. Cells with the capacity to promote blood vessel regeneration are commonly known …

New therapies for severely damaged kidneys are needed due to limited regenerative
capacity and organ donor shortages. The goal of this study was to repopulate decellularized …

Circulating endothelial colony forming cells (ECFCs) contribute to vascular repair where
they are a target for therapy. Since ECFC proliferative potential is increased in cord versus …

Background Neovascularization plays an important role in tissue engineering applications.
In animal models, it was demonstrated that implantation of endothelial progenitor cells …