[HTML][HTML] Anti-inflammatory effects of Rhodiola rosea L.: A review

W Pu, M Zhang, R Bai, L Sun, W Li, Y Yu… - Biomedicine & …, 2020 - Elsevier
Rhodiola rosea L., a worldwide botanical adaptogen, has been confirmed to possess
protective effects of inflammatory injury for many diseases, including cardiovascular …

[HTML][HTML] Progress in understanding the mechanisms of resistance to BCL-2 inhibitors

Y Xu, H Ye - Experimental Hematology & Oncology, 2022 - Springer
Venetoclax is a new type of BH3 mimetic compound that can target the binding site in the
BCL-2 protein and induce apoptosis in cancer cells by stimulating the mitochondrial …

Salidroside inhibits doxorubicin-induced cardiomyopathy by modulating a ferroptosis-dependent pathway

H Chen, J Zhu, Y Le, J Pan, Y Liu, Z Liu, C Wang… - Phytomedicine, 2022 - Elsevier
Background Doxorubicin-induced cardiotoxicity (DIC) limits the clinical application of the
drug in treatment of cancers and imposes a severe health burden on the patients. Therefore …

Polysaccharide from Rosa roxburghii Tratt Fruit Attenuates Hyperglycemia and Hyperlipidemia and Regulates Colon Microbiota in Diabetic db/db Mice

L Wang, C Li, Q Huang, X Fu - Journal of Agricultural and Food …, 2019 - ACS Publications
This study was aimed at investigating the hypoglycemic and hypolipidemic effects of a
polysaccharide (RTFP) isolated from Rosa roxburghii Tratt fruit on type-2 diabetic db/db …

[HTML][HTML] Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

L Rong, Z Li, X Leng, H Li, Y Ma, Y Chen… - Biomedicine & …, 2020 - Elsevier
Salidroside, a natural active ingredient extracted from Rhodiola rosea, has been shown to
exert antitumor activity against breast cancer Dong Young et al.[1], colon cancer Sun et al.[2] …

Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway

J Yan, C Wang, Y Jin, Q Meng, Q Liu, Z Liu, K Liu… - Pharmacological …, 2018 - Elsevier
Type 2 diabetes is characterized by insulin resistance in target tissues and hyperglycemia.
Catalpol is a natural product isolated from the root of Rehmannia glutinosa, which has been …

Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K …

Y Wang, F Chu, J Lin, Y Li, N Johnson, J Zhang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Dendrobium chrysotoxum Lindl, a well-known
traditional Chinese medicinal herb used in the treatment of gastric disease, is distinguished …

Chrysin improves glucose and lipid metabolism disorders by regulating the AMPK/PI3K/AKT signaling pathway in insulin-resistant HepG2 cells and HFD/STZ-induced …

YJ Zhou, N Xu, XC Zhang, YY Zhu… - Journal of Agricultural …, 2021 - ACS Publications
Natural products with minor side effects have been reported to be an effective adjuvant
therapy for glucose and lipid metabolism disorders. Chrysin, a flavone, has a wide range of …

Sources and implications of NADH/NAD+ redox imbalance in diabetes and its complications

J Wu, Z Jin, H Zheng, LJ Yan - Diabetes, metabolic syndrome and …, 2016 - Taylor & Francis
NAD+ is a fundamental molecule in metabolism and redox signaling. In diabetes and its
complications, the balance between NADH and NAD+ can be severely perturbed. On one …

Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice

H Xue, P Li, Y Luo, C Wu, Y Liu, X Qin, X Huang, C Sun - Phytomedicine, 2019 - Elsevier
Background Salidroside, an active component from Traditional Chinese Medicine Rhodiola
rosea L., has various pharmacological functions including anti-inflammatory, anti-cancer and …