The global burden of SLE: prevalence, health disparities and socioeconomic impact

EE Carter, SG Barr, AE Clarke - Nature reviews rheumatology, 2016 - nature.com
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can
potentially lead to serious organ complications and even death. Its global burden—in terms …

Immunomodulatory effects of diet and nutrients in systemic lupus erythematosus (SLE): a systematic review

MA Islam, SS Khandker, PJ Kotyla… - Frontiers in …, 2020 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ involvement, including the skin, joints, kidneys, lungs, central nervous system and the …

Loss of gut barrier integrity in lupus

L Ma, L Morel - Frontiers in immunology, 2022 - frontiersin.org
Systemic Lupus Erythematosus is a complex autoimmune disease and its etiology remains
unknown. Increased gut permeability has been reported in lupus patients, yet whether it …

Analysis of serum interleukin (IL)-1β and IL-18 in systemic lupus erythematosus

R Mende, FB Vincent, R Kandane-Rathnayake… - Frontiers in …, 2018 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease
characterized by biological and clinical heterogeneity. The interleukin (IL)-1 superfamily is a …

Life factors acting on systemic lupus erythematosus

J Chen, S Liao, W Pang, F Guo, L Yang, H Liu… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a highly heterogeneous autoimmune disease that
primarily affects women. Currently, in the search for the mechanisms of SLE pathogenesis …

The impact of vitamin D on the immunopathophysiology, disease activity, and extra-musculoskeletal manifestations of systemic lupus erythematosus

A Mak - International Journal of Molecular Sciences, 2018 - mdpi.com
Over the past two decades it has been increasingly recognized that vitamin D, aside from its
crucial involvement in calcium and phosphate homeostasis and the dynamics of the …

High disease activity status suggests more severe disease and damage accrual in systemic lupus erythematosus

R Koelmeyer, HT Nim, M Nikpour, YB Sun… - Lupus science & …, 2020 - lupus.bmj.com
Objective Disease severity in SLE is an important concept related to disease activity,
treatment burden and prognosis. We set out to evaluate if high disease activity status …

Role of vitamin D deficiency in systemic lupus erythematosus incidence and aggravation

T Hassanalilou, L Khalili, S Ghavamzadeh… - Autoimmunity …, 2018 - Springer
Vitamin D is one of the main groups of sterols; playing an important role in phospho-calcic
metabolism. The conversion of 7-dehydrocholesterol to pre-vitamin D3 in the skin, through …

Exploring the evidence for an immunomodulatory role of vitamin D in juvenile and adult rheumatic disease

J Zou, C Thornton, ES Chambers, EC Rosser… - Frontiers in …, 2021 - frontiersin.org
Vitamin D is synthesized in the skin following exposure to UVB radiation or is directly
absorbed from the diet. Following hydroxylation in the liver and kidneys, vitamin D becomes …

The effect of Vitamin D supplementation in disease activity of systemic lupus erythematosus patients with Vitamin D deficiency: A randomized clinical trial

H Karimzadeh, M Shirzadi… - Journal of Research in …, 2017 - journals.lww.com
Background: The aim of this study was to check the effectiveness of Vitamin D
supplementation on the disease activity of Vitamin D-deficient systemic lupus erythematosus …