The future of mechanical ventilation: lessons from the present and the past

L Gattinoni, JJ Marini, F Collino, G Maiolo, F Rapetti… - Critical Care, 2017 - Springer
The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS)
arise from two main causes: unphysiological increases of transpulmonary pressure and …

Proton pump inhibitors versus histamine 2 receptor antagonists for stress ulcer prophylaxis in critically ill patients: a systematic review and meta-analysis

W Alhazzani, F Alenezi, RZ Jaeschke… - Critical care …, 2013 - journals.lww.com
Background: Critically ill patients may develop bleeding caused by stress ulceration. Acid
suppression is commonly prescribed for patients at risk of stress ulcer bleeding. Whether …

Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal …

A Reintam Blaser, MLNG Malbrain, J Starkopf… - Intensive care …, 2012 - Springer
Purpose Acute gastrointestinal (GI) dysfunction and failure have been increasingly
recognized in critically ill patients. The variety of definitions proposed in the past has led to …

Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot study

JW Devlin, RJ Roberts, JJ Fong, Y Skrobik… - Critical care …, 2010 - journals.lww.com
Objective: To compare the efficacy and safety of scheduled quetiapine to placebo for the
treatment of delirium in critically ill patients requiring as-needed haloperidol. Design …

Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study

A Reintam Blaser, M Poeze, MLNG Malbrain… - Intensive care …, 2013 - Springer
Purpose The study aimed to develop a gastrointestinal (GI) dysfunction score predicting 28-
day mortality for adult patients needing mechanical ventilation (MV). Methods 377 adult …

Daily interruption of sedative infusions and complications of critical illness in mechanically ventilated patients

WD Schweickert, BK Gehlbach, AS Pohlman… - Critical care …, 2004 - journals.lww.com
Objective: In critically ill patients receiving mechanical ventilation, daily interruption of
sedative infusions decreases duration of mechanical ventilation and intensive care unit …

Gastrointestinal failure score in critically ill patients: a prospective observational study

A Reintam, P Parm, R Kitus, J Starkopf, H Kern - Critical care, 2008 - Springer
Introduction There are no universally accepted diagnostic criteria for gastrointestinal failure
in critically ill patients. In the present study we tested whether the occurrence of food …

Gastrointestinal symptoms in intensive care patients

A Reintam, P Parm, R Kitus, H Kern… - Acta …, 2009 - Wiley Online Library
Background: Gastrointestinal (GI) problems are not uniformly assessed in intensive care unit
(ICU) patients and respective data in available literature are insufficient. We aimed to …

Efficacy and safety of proton pump inhibitors for stress ulcer prophylaxis in critically ill patients: a systematic review and meta-analysis of randomized trials

F Alshamsi, E Belley-Cote, D Cook, SA Almenawer… - Critical Care, 2016 - Springer
Background The relative efficacy and safety of proton pump inhibitors (PPIs) compared to
histamine-2-receptor antagonists (H2RAs) should guide their use in reducing bleeding risk …

The efficacy and safety of proton pump inhibitors vs histamine-2 receptor antagonists for stress ulcer bleeding prophylaxis among critical care patients: a meta …

PC Lin, CH Chang, PI Hsu, PL Tseng… - Critical care …, 2010 - journals.lww.com
Objective: To examine the efficacy and safety of proton pump inhibitors in comparison with
histamine-2 receptor antagonists for stress-related upper gastrointestinal bleeding …