Stimuli‐responsive nanotherapeutics for precision drug delivery and cancer therapy

Y Qiao, J Wan, L Zhou, W Ma, Y Yang… - Wiley …, 2019 - Wiley Online Library
Cancer remains one of the world's leading causes of death. However, most conventional
chemotherapeutic drugs only show a narrow therapeutic window in patients because of their …

Temperature-responsive smart nanocarriers for delivery of therapeutic agents: applications and recent advances

M Karimi, P Sahandi Zangabad… - … applied materials & …, 2016 - ACS Publications
Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as
carriers that can be stimulated by changes in environmental parameters such as …

Polyurethane-based drug delivery systems

JY Cherng, TY Hou, MF Shih, H Talsma… - International journal of …, 2013 - Elsevier
Polyurethanes (PUs) are formed by a reaction between isocyanates and diols to yield
polymers with urethane bonds (–NH–COO–) in their main chain. A great variety of building …

Surface modified multifunctional and stimuli responsive nanoparticles for drug targeting: current status and uses

PI Siafaka, N Üstündağ Okur, E Karavas… - International journal of …, 2016 - mdpi.com
Nanocarriers, due to their unique features, are of increased interest among researchers
working with pharmaceutical formulations. Polymeric nanoparticles and nanocapsules …

PH responsive polyurethane for the advancement of biomedical and drug delivery

RYH Tan, CS Lee, MR Pichika, SF Cheng, KY Lam - Polymers, 2022 - mdpi.com
Due to the specific physiological pH throughout the human body, pH-responsive polymers
have been considered for aiding drug delivery systems. Depending on the surrounding pH …

Doxorubicin nanoformulations on therapy against cancer: An overview from the last 10 years

NA D'Angelo, MA Noronha, MCC Câmara… - Biomaterials …, 2022 - Elsevier
Doxorubicin (DOX) is a natural antibiotic with antineoplastic activity. It has been used for
over 40 years and remains one of the most used drugs in chemotherapy for a variety of …

Stimuli‐responsive polymeric nanoparticles for nanomedicine

CIC Crucho - ChemMedChem, 2015 - Wiley Online Library
Nature continues to be the ultimate in nanotechnology, where polymeric nanometer‐scale
architectures play a central role in biological systems. Inspired by the way nature forms …

Nanobiocatalyst advancements and bioprocessing applications

M Misson, H Zhang, B Jin - Journal of the Royal Society …, 2015 - royalsocietypublishing.org
The nanobiocatalyst (NBC) is an emerging innovation that synergistically integrates
advanced nanotechnology with biotechnology and promises exciting advantages for …

Surface functionalization of biomaterials by radical polymerization

T Zhou, Y Zhu, X Li, X Liu, KWK Yeung, S Wu… - Progress in Materials …, 2016 - Elsevier
One effective strategy in the field of biomaterials is to develop biomimetic interfaces to
modulate the cell behavior and promote tissue regeneration and surface modification is the …

Biofunctionalized polymer-lipid supported mesoporous silica nanoparticles for release of chemotherapeutics in multidrug resistant cancer cells

X Zhang, F Li, S Guo, X Chen, X Wang, J Li, Y Gan - Biomaterials, 2014 - Elsevier
Multidrug resistance (MDR) is a major impediment to the success of cancer chemotherapy. A
polymer-lipid supported mesoporous silica nanoparticle (PLS-MSNs) is described here to …