Renal diseases and the role of complement: linking complement to immune effector pathways and therapeutics

T Freiwald, B Afzali - Advances in immunology, 2021 - Elsevier
The complement system is an ancient and phylogenetically conserved key danger sensing
system that is critical for host defense against pathogens. Activation of the complement …

Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis

HR Gouda, IM Talaat, A Bouzid, H El-Assi… - Frontiers in …, 2022 - frontiersin.org
Glomerulonephritis (GN) is a complex disease with intricate underlying pathogenic
mechanisms. The possible role of underlying complement dysregulation is not fully …

Case report: A pediatric case of MPO-ANCA-associated granulomatosis with polyangiitis superimposed on post-streptococcal acute glomerulonephritis

Q Kuang, X He, L Jia, Z Zhang, C Gui, C Gao… - Frontiers in …, 2023 - frontiersin.org
An eight-year-old girl was admitted with vomiting, gross hematuria, and progressive renal
dysfunction. A renal biopsy revealed endocapillary proliferative glomerulopathy and …

[HTML][HTML] Атипичный гемолитико-уремический синдром при гломерулопатиях. Клиническое наблюдение и краткий обзор литературы

НЛ Козловская, ЮВ Коротчаева, КА Демьянова - Нефрология, 2020 - cyberleninka.ru
По современным представлениям, для развития атипичного гемолитико-уремического
синдрома (аГУС) у предрасположенных лиц необходимо воздействие дополнительных …

Atypical hemolytic-uremic syndrome and glomerulopathies. Clinical observation and a brief literature review

NL Kozlovskaya, YV Korotchaeva… - Nephrology (Saint …, 2020 - journal.nephrolog.ru
According to modern concepts, for the development of atypical hemolytic uremic syndrome
(aHUS) in predisposed individuals, additional factors are necessary, which today are …

[引用][C] reproduce the human clinical picture (Pickering et al., 2007; Smith-Jackson et al., 2019; Ueda et al., 2017). The role of complement factors expressed locally …

T Freiwald, B Afzali - Advances in Immunology, 2021 - Elsevier