[HTML][HTML] The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

[HTML][HTML] Zika virus vaccines

P Abbink, KE Stephenson, DH Barouch - Nature Reviews Microbiology, 2018 - nature.com
The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …

[HTML][HTML] Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

F Aubry, S Jacobs, M Darmuzey, S Lequime… - Nature …, 2021 - nature.com
The global emergence of Zika virus (ZIKV) revealed the unprecedented ability for a mosquito-
borne virus to cause congenital birth defects. A puzzling aspect of ZIKV emergence is that all …

[HTML][HTML] An immunocompetent mouse model of Zika virus infection

MJ Gorman, EA Caine, K Zaitsev, MC Begley… - Cell host & …, 2018 - cell.com
Progress toward understanding Zika virus (ZIKV) pathogenesis is hindered by lack of
immunocompetent small animal models, in part because ZIKV fails to effectively antagonize …

[HTML][HTML] Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice

B Cao, LA Parnell, MS Diamond… - Journal of Experimental …, 2017 - rupress.org
Zika virus (ZIKV) infection during pregnancy leads to devastating fetal outcomes, including
intrauterine growth restriction and microcephaly. Greater understanding of mechanisms …

[HTML][HTML] Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

SM Nguyen, KM Antony, DM Dudley, S Kohn… - PLoS …, 2017 - journals.plos.org
Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

[HTML][HTML] Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms

R Fekete, C Cserép, N Lénárt, K Tóth, B Orsolits… - Acta …, 2018 - Springer
Neurotropic herpesviruses can establish lifelong infection in humans and contribute to
severe diseases including encephalitis and neurodegeneration. However, the mechanisms …

Modes of transmission of Zika virus

CJ Gregory, T Oduyebo, AC Brault… - The Journal of …, 2017 - academic.oup.com
Abstract For> 60 years, Zika virus (ZIKV) has been recognized as an arthropod-borne virus
with Aedes species mosquitoes as the primary vector. However in the past 10 years, multiple …

[HTML][HTML] Consequences of viral infection and cytokine production during pregnancy on brain development in offspring

D Elgueta, P Murgas, E Riquelme, G Yang… - Frontiers in …, 2022 - frontiersin.org
Infections during pregnancy can seriously damage fetal neurodevelopment by aberrantly
activating the maternal immune system, directly impacting fetal neural cells. Increasing …

[HTML][HTML] Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy

JA Regla-Nava, A Elong Ngono, KM Viramontes… - Nature …, 2018 - nature.com
As Zika virus (ZIKV) emerges into Dengue virus (DENV)-endemic areas, cases of ZIKV
infection in DENV-immune pregnant women may rise. Here we show that prior DENV …