Deep learning in histopathology: the path to the clinic

J Van der Laak, G Litjens, F Ciompi - Nature medicine, 2021 - nature.com
Abstract Machine learning techniques have great potential to improve medical diagnostics,
offering ways to improve accuracy, reproducibility and speed, and to ease workloads for …

[HTML][HTML] Digital pathology and artificial intelligence in translational medicine and clinical practice

V Baxi, R Edwards, M Montalto, S Saha - Modern Pathology, 2022 - Elsevier
Traditional pathology approaches have played an integral role in the delivery of diagnosis,
semi-quantitative or qualitative assessment of protein expression, and classification of …

Deep learning in cancer pathology: a new generation of clinical biomarkers

A Echle, NT Rindtorff, TJ Brinker, T Luedde… - British journal of …, 2021 - nature.com
Clinical workflows in oncology rely on predictive and prognostic molecular biomarkers.
However, the growing number of these complex biomarkers tends to increase the cost and …

The role of artificial intelligence in early cancer diagnosis

B Hunter, S Hindocha, RW Lee - Cancers, 2022 - mdpi.com
Simple Summary Diagnosing cancer at an early stage increases the chance of performing
effective treatment in many tumour groups. Key approaches include screening patients who …

[HTML][HTML] Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts

S Haggenmüller, RC Maron, A Hekler, JS Utikal… - European Journal of …, 2021 - Elsevier
Background Multiple studies have compared the performance of artificial intelligence (AI)–
based models for automated skin cancer classification to human experts, thus setting the …

Pan-cancer integrative histology-genomic analysis via multimodal deep learning

RJ Chen, MY Lu, DFK Williamson, TY Chen, J Lipkova… - Cancer Cell, 2022 - cell.com
The rapidly emerging field of computational pathology has demonstrated promise in
developing objective prognostic models from histology images. However, most prognostic …

Artificial intelligence for digital and computational pathology

AH Song, G Jaume, DFK Williamson, MY Lu… - Nature Reviews …, 2023 - nature.com
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …

Artificial intelligence as the next step towards precision pathology

B Acs, M Rantalainen, J Hartman - Journal of internal medicine, 2020 - Wiley Online Library
Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic
diagnosis of cancer is increasing as personalized cancer therapy requires accurate …

Artificial intelligence assists precision medicine in cancer treatment

J Liao, X Li, Y Gan, S Han, P Rong, W Wang… - Frontiers in …, 2023 - frontiersin.org
Cancer is a major medical problem worldwide. Due to its high heterogeneity, the use of the
same drugs or surgical methods in patients with the same tumor may have different curative …

Using machine learning algorithms to predict immunotherapy response in patients with advanced melanoma

P Johannet, N Coudray, DM Donnelly, G Jour… - Clinical Cancer …, 2021 - AACR
Purpose: Several biomarkers of response to immune checkpoint inhibitors (ICI) show
potential but are not yet scalable to the clinic. We developed a pipeline that integrates deep …