Animals receive environmental stimuli from neural signals in order to produce hormones that
control immune responses. Glucocorticoids (GCs) are a group of steroid hormones …

In various human diseases, an increase in capillary permeability to proteins leads to the loss
of protein-rich fluid from the intravascular to the interstitial space. Although sepsis is the …

The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite
that, it remains controversial as to what purpose GCs serve at such times. One view …

Chronic liver inflammation drives hepatic fibrosis, and current immunosuppressive, anti-
inflammatory, and anti-viral therapies can weaken this driver. Hepatic fibrosis is reversed …

Background Lower respiratory tract infections are often treated with antibiotics without
evidence of clinically relevant bacterial disease. Serum calcitonin precursor concentrations …

Philosopher, sociologist and urban theorist, Henri Lefebvre is one of the great social
theorists of the twentieth century. This accessible and innovative introduction to the work of …

Glucocorticoids have pleiotropic effects that are used to treat diverse diseases such as
asthma, rheumatoid arthritis, systemic lupus erythematosus and acute kidney transplant …

The inflammatory response is a highly regulated physiological process that is critically
important for homeostasis. A precise physiological control of inflammation allows a timely …

Glucocorticoids are small lipophilic compounds that mediate their many biological effects by
binding an intracellular receptor (GR) that, in turn, translocates to the nucleus and directly or …

Glucocorticoid synthesis is a complex, multistep process that starts with cholesterol being
delivered to the inner membrane of mitochondria by StAR and StAR-related proteins. Here …