MicroRNA-27a reduces mutant hutingtin aggregation in an in vitro model of Huntington's disease

JJ Ban, JY Chung, M Lee, W Im, M Kim - Biochemical and biophysical …, 2017 - Elsevier
Huntington's disease (HD) is a fatal genetic disease caused by abnormal aggregation of
mutant huntingtin protein (mHtt). Reduction of mHtt aggregation decreases cell death of the …

Adult stem cell response to doped bioactive borate glass

NJ Thyparambil, LC Gutgesell, CC Hurley… - Journal of Materials …, 2020 - Springer
Bioactive glasses have transformed healthcare due to their versatility. Bioactive borate
glass, in particular, has shown remarkable healing properties for both hard and soft tissues …

Intravenous administration of adipose‐derived stem cell protein extracts improves neurological deficits in a rat model of stroke

K Zhao, R Li, C Gu, L Liu, Y Jia, X Guo… - Stem cells …, 2017 - Wiley Online Library
Treatment of adipose‐derived stem cell (ADSC) substantially improves the neurological
deficits during stroke by reducing neuronal injury, limiting proinflammatory immune …

Cytosolic extract of human adipose stem cells reverses the amyloid beta-induced mitochondrial apoptosis via P53/Foxo3a pathway

T Liu, M Lee, JJ Ban, W Im, I Mook-Jung, M Kim - PloS one, 2017 - journals.plos.org
Human adipose stem cells (hASC) have therapeutic potential for the treatment of
neurodegenerative disorders. Mitochondrial dysfunction is frequently observed in most …

Adipose-derived stromal cells enhance auditory neuron survival in an animal model of sensory hearing loss

P Schendzielorz, M Vollmer, K Rak, A Wiegner, N Nada… - Cytotherapy, 2017 - Elsevier
Background A cochlear implant (CI) is an electronic prosthesis that can partially restore
speech perception capabilities. Optimum information transfer from the cochlea to the central …

脂肪干细胞对神经创伤修复的研究进展*

刘亚楠, 路莉, 王学习, 吴勇杰, 刘霞 - 中国生物工程杂志, 2018 - manu60.magtech.com.cn
在医学上, 神经系统对神经损伤的自我修复能力往往有限. 因此, 探索有效修复损伤神经的方法
已经成为近年来的研究热点. 研究发现脂肪干细胞对各类损伤神经都有一定的修复作用 …

Stem Cell Therapy for Neurovascular and Traumatic Brain Diseases

MG Crowley, M Grant Liska, CV Borlongan - Cell Therapy: Current Status …, 2017 - Springer
Diseases of the neurovascular unit, consisting of the endothelial vasculature and supporting
cells, are incredibly prevalent in patients. Two such diseases, stroke and traumatic brain …