Motivation Gene regulation is responsible for controlling numerous physiological functions
and dynamically responding to environmental fluctuations. Reconstructing the human …

Existing evidence indicates that gut fungal dysbiosis might play a key role in the
pathogenesis of colorectal cancer (CRC). We sought to explore whether reversing the fungal …

The histone methyltransferase EZH2 silences gene expression via H3 lysine 27
trimethylation and has been recognized as an important antitumour therapeutic target …

The reprogramming of cellular metabolism is a hallmark of tumorigenesis. However, the
prognostic value of metabolism-related genes in colon cancer remains unclear. This study …

Advanced prostate cancers frequently develop resistance to androgen-deprivation therapy
with serious implications for patient survival. Considering their importance in this type of …

Gastric cancer (GC) is one of the most lethal malignant tumors; the resistance of this type of
tumor is the main source of GC treatment failure. In this study, we used bioinformatics …

Terbinafine is used for the treatment of several superficial fungal infections. In silico
analyses and animal models suggest that terbinafine might have an anti‐tumor effect. We …

Metabolic reprogramming is a hallmark of cancer. It has been described that breast cancer
subtypes present metabolism differences and this fact enables the possibility of using …

Liver cancer is considered the sixth most commonly diagnosed cancer and the fourth
leading cause of cancer-related deaths worldwide. Currently, there is no specific and …

Biology, from the ancient Greek,“study of life”, is the most fascinating yet complex of all
sciences. Its understanding is paramount in solving many current problems we face in our …