Uterine Transcriptome: Understanding Physiology and Disease Processes

GW Kirschen, K Hessami, A AlAshqar, S Afrin… - Biology, 2023 - mdpi.com
Simple Summary RNA sequencing of the human endometrium and myometrium during
normal menstruation and in gynecological disorders including endometriosis, adenomyosis …

[HTML][HTML] Bioengineering approaches for the endometrial research and application

W Dai, J Liang, R Guo, Z Zhao, Z Na, D Xu, D Li - Materials Today Bio, 2024 - Elsevier
The endometrium undergoes a series of precise monthly changes under the regulation of
dynamic levels of ovarian hormones that are characterized by repeated shedding and …

The effect of obesity on uterine receptivity is mediated by endometrial extracellular vesicles that control human endometrial stromal cell decidualization and …

L Galio, L Bernet, Y Rodriguez… - Journal of …, 2023 - Wiley Online Library
The objectives of the present study were to determine whether obesity impacts human
decidualization and the endometrial control of trophoblast invasion (both of which are …

Development of polarity-reversed endometrial epithelial organoids

V Ahmad, SGR Yeddula, BP Telugu… - …, 2024 - rep.bioscientifica.com
In brief Polarity-reversed endometrial epithelial organoids exhibit histological and
physiological characteristics resembling uterine epithelium in vivo, respond to hormones …

Using organoids to investigate human endometrial receptivity

J Guo, W Zhou, M Sacco, P Downing… - Frontiers in …, 2023 - frontiersin.org
The human endometrium is only receptive to an implanting blastocyst in the mid-secretory
phase of each menstrual cycle. Such time-dependent alterations in function require intricate …

Human receptive endometrial organoid for deciphering the implantation window

Y Zhang, R Zhao, C Yang, J Song, P Liu, Y Li, B Liu… - bioRxiv, 2023 - biorxiv.org
Human endometrial receptivity is a critical determinant of pregnancy success; however, in
vivo studies of its features and regulation are particularly challenging due to ethical …

[HTML][HTML] Deciphering endometrial dysfunction in patients with uterine myoma using endometrial organoids: a pilot study

Y Zhang, M Lu, Y Han, B Liu, R Zhao, P Liu… - Reproductive …, 2024 - Elsevier
Abstract Research Question What kind of influence does intramural myoma have on the
endometrium, and how does it take action? Design Endometrium was collected from 13 …

Polycystic ovary syndrome and adverse pregnancy outcomes: potential role of decidual function

L Li, H Ge, J Zhou, J Wang, L Wang - Drug Discoveries & …, 2023 - jstage.jst.go.jp
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting fertility and
mental health among women of reproductive age. In addition to anovulation and …