The synaptic hypothesis of schizophrenia has been highly influential. However, new
approaches mean there has been a step-change in the evidence available, and some tenets …

Psychiatry, as a field, lacks objective markers for diagnosis, progression, treatment planning,
and prognosis, in part due to difficulties studying the brain in vivo, and diagnoses are based …

Although many studies on brain-age prediction in patients with schizophrenia have been
reported recently, none has predicted brain age based on different neuroimaging modalities …

Childhood maltreatment has been suggested to have an adverse impact on
neurodevelopment, including microstructural brain abnormalities. Existing neuroimaging …

BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a clinically heterogeneous
neurodevelopmental disorder defined by characteristic behavioral and cognitive features …

Abstract Background and Hypothesis Disrupted control of brain state transitions may
contribute to the diverse dysfunctions of cognition, emotion, and behavior that are …

Current strategies to predict psychosis identify only a small proportion of individuals at risk.
Additional strategies are needed to increase capacity for prediction and prevention of …

Tract-specific microstructural analysis of the brain's white matter (WM) using diffusion MRI
has been a driver for neuroscientific discovery with a wide range of applications. Tractometry …

Importance The lack of robust neuroanatomical markers of psychosis risk has been
traditionally attributed to heterogeneity. A complementary hypothesis is that variation in …

The neurobiology of catatonia is still poorly understood. Particularly structural MRI studies
yielded conflicting results. Heterogeneity of findings was suggested to stem from specifics of …