Much evidence shows that physical exercise (PE) is a strong gene modulator that induces
structural and functional changes in the brain, determining enormous benefit on both …

Running, and aerobic exercise in general, is a physical activity that increasingly many
people engage in but that also has become popular as a topic for scientific research. Here …

The endocannabinoid system (ECS) is involved in various processes, including brain
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …

As human life expectancy increases, cognitive decline and memory impairment threaten
independence and quality of life. Therefore, finding prevention and treatment strategies for …

Multiple sclerosis is the most common inflammatory demyelinating disease of the central
nervous system, caused by an autoimmune response against myelin that eventually leads to …

The mammalian brain stores and distinguishes among episodic memories, ie memories
formed during the personal experience, through a mechanism of pattern separation …

The CB 1 cannabinoid receptor, the main molecular target of endocannabinoids and
cannabis active components, is the most abundant G protein-coupled receptor in the …

Regular physical exercise enhances memory functions, synaptic plasticity in the
hippocampus, and brain derived neurotrophic factor (BDNF) levels. Likewise, short periods …

Dentate gyrus of the hippocampus continuously gives rise to new neurons, namely, adult-
born granule cells, which contribute to conferring plasticity to the mature brain throughout …

We assessed the antidepressant-like effects of environmental enrichment (EE) and physical
exercise (PE) compared with the selective serotonin reuptake inhibitor fluoxetine against the …