Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …

Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …

Potent and selective antifungal agents are urgently needed due to the quick increase of
serious invasive fungal infections and the limited antifungal drugs available. Microbial …

Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout
nature. As they participate in a number of different aspects of innate immunity in mammals …

Chronic wound infections have caused an increasing number of deaths and economic
burden, which necessitates wound treatment options. Hitherto, the development of functional …

Infections caused by invasive fungal biofilms have been widely associated with high
morbidity and mortality rates, mainly due to the advent of antibiotic resistance. Moreover …

Host defense peptides are expressed in various immune cells, including phagocytic cells
and epithelial cells. These peptides selectively alter innate immune pathways in response to …

Ocular infection induced by bacteria and fungi is a major cause of visual impairment and
blindness. Topical administration of antibiotics remains the first-line treatment, as effective …

Oral epithelial cells (OECs) represent the first line of defense against viruses that are spread
via saliva, including Kaposi's sarcoma-associated herpesvirus (KSHV). Infection of humans …