Malignant pleural mesothelioma: history, controversy, and future of a man-made epidemic

OD Røe, GM Stella - Asbestos and Mesothelioma, 2017 - Springer
Asbestos (Greek, inextinguishable) is the term of a family of naturally occurring minerals that
have been used in small scale since ancient times. Industrialization demanded increased …

Inherited genetic mutations and polymorphisms in malignant mesothelioma: a comprehensive review

V Panou, OD Røe - International journal of molecular sciences, 2020 - mdpi.com
Malignant mesothelioma (MM) is mainly caused by air-born asbestos but genetic
susceptibility is also suspected to be a risk factor. Recent studies suggest an increasing …

Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos‐and histology‐related changes in lung cancer

P Nymark, M Guled, I Borze, A Faisal… - Genes …, 2011 - Wiley Online Library
Lung cancer has the highest mortality rate of all of the cancers in the world and asbestos‐
related lung cancer is one of the leading occupational cancers. The identification of …

[HTML][HTML] Germline mutations in DNA repair genes predispose asbestos-exposed patients to malignant pleural mesothelioma

M Betti, E Casalone, D Ferrante, A Aspesi, G Morleo… - Cancer letters, 2017 - Elsevier
Malignant pleural mesothelioma (MPM) is a rare, aggressive cancer caused by asbestos
exposure. An inherited predisposition has been suggested to explain multiple cases in the …

Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy

H Li, KW Peng, D Dingli, RA Kratzke, SJ Russell - Cancer gene therapy, 2010 - nature.com
Mesothelioma usually leads to death within 8–14 months of diagnosis. To increase the
potency of oncolytic measles viruses (MVs) for mesothelioma therapy, we inserted the …

Sensitivity to asbestos is increased in patients with mesothelioma and pathogenic germline variants in BAP1 or other DNA repair genes

M Betti, A Aspesi, D Ferrante, M Sculco… - Genes …, 2018 - Wiley Online Library
Pathogenic germline variants in the BAP1 tumor suppressor gene can cause a cancer
syndrome called BAP1 tumor predisposition syndrome (BAP1‐TPDS), which is …

Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high‐risk area

M Betti, E Casalone, D Ferrante… - Genes …, 2015 - Wiley Online Library
Inherited loss‐of‐function mutations in the BAP1 oncosuppressor gene are responsible for
an inherited syndrome with predisposition to malignant mesothelioma (MM), uveal and …

Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells

Y Sekido - Cancer science, 2010 - Wiley Online Library
Malignant mesothelioma (MM) is a tumor with poor prognosis associated with asbestos
exposure. While it remains to be clarified how asbestos fibers confer genetic/epigenetic …

[图书][B] Asbestos: risk assessment, epidemiology, and health effects

RF Dodson, SP Hammar - 2005 - taylorfrancis.com
While there are hundreds of books available on many different aspects of asbestos, none
contain the encyclopedic, comprehensive coverage you will find here. Edited by leading …

Second Italian consensus conference on malignant pleural mesothelioma: state of the art and recommendations

C Pinto, S Novello, V Torri, A Ardizzoni, PG Betta… - Cancer treatment …, 2013 - Elsevier
Malignant pleural mesothelioma (MPM) is a relevant public health issue. A large amount of
data indicate a relationship between mesothelioma and asbestos exposure. MPM incidence …