The crystallins were discovered more than 100 years ago by Mörner (1893. Untersuchungen
der Proteinsubstanzen in den lichtbrechenden Medien des Auges. Z. Physiol. Chem. 18, 61 …

The primary function of the lens resides in its transparency and ability to focus light on the
retina. These require both that the lens cells contain high concentrations of densely packed …

We are exploring the mechanisms underlying how maternal infection increases the risk for
schizophrenia and autism in the offspring. Several mouse models of maternal immune …

Conspectus Crystallins are transparent, refractive proteins that contribute to the focusing
power of the vertebrate eye lens. These proteins are extremely soluble and resist …

Scandium radionuclides have been identified in the late 1990s as promising for nuclear
medicine applications, but have been set aside for about 20 years. Among the different …

Elucidation of the energetic principles of binding affinity and specificity is a central task in
many branches of current sciences: biology, medicine, pharmacology, chemistry, material …

The βγ-crystallin superfamily consists of evolutionarily related proteins with domain topology
similar to lens β-and γ-crystallins, formed from duplicated Greek key motifs. Ca2+ binding …

The βγ-crystallin superfamily contains both β-and γ-crystallins of the vertebrate eye lens and
the microbial calcium-binding proteins, all of which are characterized by a common double …

βγ-Crystallin-type double clamp (N/D)(N/D) XX (S/T) S motif is an established but sparsely
investigated motif for Ca 2+ binding. A βγ-crystallin domain is formed of two Greek key …

The lens is an avascular organ whose function and survival depend on an internal
circulation system. Cx46fs380 mice model a human autosomal dominant cataract caused by …