KLF13 loss‐of‐function mutations underlying familial dilated cardiomyopathy

YH Guo, J Wang, XJ Guo, RF Gao… - Journal of the …, 2022 - Am Heart Assoc
Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular
enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a …

Gene mutations in comorbidity of epilepsy and arrhythmia

C Yu, X Deng, D Xu - Journal of neurology, 2023 - Springer
Epilepsy is one of the most common neurological disorders, and sudden unexpected death
in epilepsy (SUDEP) is the most severe outcome of refractory epilepsy. Arrhythmia is one of …

Autopsy of all young sudden death cases is important to increase survival in family members left behind

TH Lynge, CM Albert, C Basso, R Garcia… - EP …, 2024 - academic.oup.com
Sudden cardiac death (SCD) is an important public health problem worldwide, accounting
for an estimated 6–20% of total mortality. A significant proportion of SCD is caused by …

Cardiovascular Disease Burden, Mortality, and Sudden Death Risk in Epilepsy: A UK Biobank Study

RA Shah, CAA Chahal, S Ranjha, GS Dabbagh… - Canadian Journal of …, 2024 - Elsevier
Background Sudden death is the leading cause of mortality in medically refractory epilepsy.
Middle-aged persons with epilepsy (PWE) are under investigated regarding their mortality …

Challenges in decoding sudden unexpected death in epilepsy: The intersection between heart and brain in epilepsy

B Asatryan - Journal of the American Heart Association, 2021 - Am Heart Assoc
Patients with epilepsy are at least 2-to 3-fold higher risk for dying prematurely and suddenly
than the general population. 1–3 When an unexpected, nontraumatic and nondrowning …

Known pathogenic gene variants and new candidates detected in sudden unexpected infant death using whole genome sequencing

AM Bard, LV Clark, E Cosgun… - American Journal of …, 2024 - Wiley Online Library
The purpose of this study is to gain insights into potential genetic factors contributing to the
infant's vulnerability to Sudden Unexpected Infant Death (SUID). Whole Genome …

Known pathogenic gene variants and new candidates detected in Sudden Unexpected Infant Death (SUID) using Whole Genome Sequencing (WGS)

AM Bard, LV Clark, E Cosgun, KA Aldinger, A Timms… - medRxiv, 2023 - medrxiv.org
Purpose In this study we performed WGS of children that succumbed to SUID during their
first year of life to gain insights into potential genetic risk factors that could contribute to an …

Sudden Unexpected Death in Epilepsy (SUDEP). Full forensic approach in two cases and review of literature

T Biondo, G Baldino, G Burrascano… - La Clinica …, 2024 - clinicaterapeutica.it
Background. The SUDEP is defined as a sudden unexpected death in patients affected by
epilepsy, with or without evidence of a seizure, excluding documented status epilepticus, in …

The analysis of SUDEP forensic autopsies leading to preventable events

A Argo, M Puntarello, G Malta, R Buscemi… - Frontiers in …, 2023 - frontiersin.org
Introduction The diagnosis of unexpected death by excluding non-natural causes,
particularly in subjects with epilepsy, is a topic of interest and it is difficult to identify in the …

Mortality and Sudden death risk in middle-aged persons with epilepsy—a UK Biobank study

RA Shah, CAA Chahal, S Ranjha, GS Dabbagh… - medRxiv, 2023 - medrxiv.org
Background Sudden death is the leading cause of mortality in medically refractory cases of
epilepsy. Younger persons with epilepsy (PWE), particularly those< 40 years, have higher …