[HTML][HTML] The benefit of a complete reference genome for cancer structural variant analysis
The complexities of cancer genomes are becoming more easily interpreted due to
advancements in sequencing technologies and improved bioinformatic analysis. Structural …
advancements in sequencing technologies and improved bioinformatic analysis. Structural …
Development of an Automated, Ultra-Rapid Bottom-Up Proteomics Workflow Utilizing Alginate-Based Hydrogels
A new approach to sample preparation and enzymatic digestion in bottom-up proteomics
has been developed using alginate-based hydrogel entrapment of enzymes. This hydrogel …
has been developed using alginate-based hydrogel entrapment of enzymes. This hydrogel …
[HTML][HTML] Characterization of the Rat Osteosarcoma Cell Line UMR-106 by Long-Read Technologies Identifies a Large Block of Amplified Genes Associated with …
AF Scott, DW Mohr, WA Littrell, R Babu, M Kokosinski… - Genes, 2024 - mdpi.com
Background/Objectives: The rat osteosarcoma cell line UMR-106 is widely used for the study
of bone cancer biology but it has not been well characterized with modern genomic …
of bone cancer biology but it has not been well characterized with modern genomic …
[HTML][HTML] Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long reads
A Keskus, A Bryant, T Ahmad, B Yoo, S Aganezov… - medRxiv, 2024 - ncbi.nlm.nih.gov
Most current studies rely on short-read sequencing to detect somatic structural variation (SV)
in cancer genomes. Long-read sequencing offers the advantage of better mappability and …
in cancer genomes. Long-read sequencing offers the advantage of better mappability and …
The benefit of a complete reference genome for cancer structural variant analysis
The complexities of cancer genomes are becoming more easily interpreted due to
advancements in sequencing technologies and improved bioinformatic analysis. Structural …
advancements in sequencing technologies and improved bioinformatic analysis. Structural …
Allele imbalance in mRNA is selected in tumorigenesis, results from epigenetic alterations and has prognostic relevance
G Palou-Márquez, P Pericot-Masdevall, F Supek - bioRxiv, 2024 - biorxiv.org
Allele-specific expression (ASE) is the differential abundance in levels of mRNAs that
originated from the paternal and maternal copies of a gene. Such allelic imbalances can …
originated from the paternal and maternal copies of a gene. Such allelic imbalances can …
[PDF][PDF] Allele-specific expression is selected in tumorigenesis, results from epigenetic changes and has prognostic relevance
G Palou-Márquez, P Pericot-Masdevall, F Supek - biorxiv.org
Allele-specific expression (ASE) is the differential abundance in levels of mRNAs that
originated from the paternal and maternal copies of a gene. Such allelic imbalances can …
originated from the paternal and maternal copies of a gene. Such allelic imbalances can …