Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

B Chen, P Yu, WN Chan, F Xie, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

Roles of zinc in cancers: from altered metabolism to therapeutic applications

M Bendellaa, P Lelièvre, JL Coll… - … Journal of Cancer, 2024 - Wiley Online Library
Zinc (Zn) is a crucial trace element involved in various cellular processes, including
oxidative stress, apoptosis and immune response, contributing to cellular homeostasis …

scTIGER: A Deep-Learning Method for Inferring Gene Regulatory Networks from Case versus Control scRNA-seq Datasets

M Dautle, S Zhang, Y Chen - International Journal of Molecular Sciences, 2023 - mdpi.com
Inferring gene regulatory networks (GRNs) from single-cell RNA-seq (scRNA-seq) data is an
important computational question to find regulatory mechanisms involved in fundamental …

Emerging Perspectives in Zinc Transporter Research in Prostate Cancer: An Updated Review

S Acevedo, MF Segovia, E de la Fuente-Ortega - Nutrients, 2024 - mdpi.com
Dysregulation of zinc and zinc transporters families has been associated with the genesis
and progression of prostate cancer. The prostate epithelium utilizes two types of zinc …

Effects of dextran-graft-polyacrylamide/ZnO nanoparticles on prostate cancer cell lines in vitro

PA Virych, TV Zadvornyi, TV Borikun… - Experimental …, 2022 - exp-oncology.com.ua
Background: The combination of zinc oxide (ZnO) nanoparticles (NPs) with carriers
enhances the anticancer effect of nanocomposites. Aim: To explore the mechanisms of …

scTIGER: A Deep-Learning Method for Inferring Gene Regulatory Networks From Single-Cell Gene Expression Data

MA Dautle - 2023 - search.proquest.com
Inferring gene regulatory networks (GRNs) from single-cell RNA-sequencing (scRNA-seq)
data is an important computational question to reveal fundamental regulatory mechanisms …