Pleasurable and problematic receptive anal intercourse and diseases of the colon, rectum and anus

DR Dickstein, CR Edwards, CR Rowan… - Nature Reviews …, 2024 - nature.com
The ability to experience pleasurable sexual activity is important for human health.
Receptive anal intercourse (RAI) is a common, though frequently stigmatized, pleasurable …

Association between rectal douching and HIV and other sexually transmitted infections among men who have sex with men: a systematic review and meta-analysis

P Li, T Yuan, T Fitzpatrick, K Smith, J Zhao… - Sexually transmitted …, 2019 - sti.bmj.com
Background Men who have sex with men (MSM) are disproportionately affected by HIV and
other STIs worldwide. Rectal douching, which is commonly used by MSM in preparation for …

A randomized trial of safety, acceptability and adherence of three rectal microbicide placebo formulations among young sexual and gender minorities who engage in …

JA Bauermeister, C Dominguez Islas, Y Jiao, R Tingler… - Plos one, 2023 - journals.plos.org
Efforts to develop a range of HIV prevention products that can serve as behaviorally
congruent viable alternatives to consistent condom use and oral pre-exposure prophylaxis …

Twinks, Jocks, and Bears, Oh My! Differing subcultural appearance identifications among gay men and their associated eating disorder psychopathology

SM Fogarty, DC Walker - Body Image, 2022 - Elsevier
Gay men have increased risk of body dissatisfaction and disordered eating compared to
heterosexual men, and it is unclear what differentiates their risk for thinness-and muscularity …

Pharmacokinetics and efficacy of topical inserts containing tenofovir alafenamide fumarate and elvitegravir administered rectally in macaques

N Makarova, T Singletary, MM Peet, J Mitchell… - …, 2022 - thelancet.com
Background Topical on-demand forms for HIV pre-exposure prophylaxis (PrEP) may be a
desirable alternative for people that prefer not to use daily PrEP. CONRAD has developed …

Sexual health and treatment-related sexual dysfunction in sexual and gender minorities with prostate cancer

DR Dickstein, CR Edwards, EJ Lehrer… - Nature Reviews …, 2023 - nature.com
Prostate cancer treatment has substantial effects on sexual health and function. Sexual
function is a vital aspect of human health and a critical component of cancer survivorship …

HIV antiretroviral pre‐exposure prophylaxis: development challenges and pipeline promise

CW Hendrix - Clinical Pharmacology & Therapeutics, 2018 - Wiley Online Library
The US Food and Drug Administration (FDA) approved oral daily tenofovir/emtricitabine
(Truvada) for pre‐exposure prophylaxis of human immunodeficiency virus (HIV) infection in …

Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema

T Hoang, AA Date, JO Ortiz, TW Young… - European Journal of …, 2019 - Elsevier
HIV pre-exposure prophylaxis (PrEP) strategies have the potential to prevent millions of
incident HIV infections each year. However, the efficacy of PrEP strategies has been …

Rectal douching practices associated with anal intercourse: implications for the development of a behaviorally congruent HIV-prevention rectal microbicide douche

A Carballo-Dieguez, R Giguere, C Lentz, C Dolezal… - AIDS and Behavior, 2019 - Springer
Tenofovir administration via rectal douching results in higher rectal-mucosa drug
concentration than oral administration. Many who engage in receptive anal intercourse (RAI) …

Getting clear about rectal douching among men who have sex with men

C Grov, D Westmoreland, PB Carneiro… - Archives of sexual …, 2021 - Springer
Receptive anal sex is the primary means through which HIV is transmitted among men who
have sex with men (MSM). Recently, researchers have begun investigating the role that …