Liver diseases related complications represent a significant source of morbidity and mortality
worldwide, creating a substantial economic burden. Oxidative stress, excessive …

The prevalence of nonalcoholic fatty liver disease (NAFLD) has been significantly increased
due to the global epidemic of obesity. The disease progression from simple steatosis (NAFL) …

Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the
progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte …

Background & Aims Inflammation affects regeneration of the intestinal epithelia; long
noncoding RNAs (lncRNAs) regulate cell functions, such as proliferation, differentiation, and …

Many studies have revealed that circulating long noncoding RNAs (lncRNAs) regulate gene
and protein expression in the process of hepatic fibrosis. Liver fibrosis is a reversible wound …

Idiosyncratic drug‐induced liver injury (DILI) is a rare, often difficult‐to‐predict adverse
reaction with complex pathomechanisms. However, it is now evident that certain forms of …

Activation of hepatic macrophages represents the critical driving force to promote cholestatic
liver injury. Exosomes, as important small extracellular vesicles released by almost all types …

Chronic cholestatic liver diseases, such as primary biliary cholangitis (PBC) and primary
sclerosing cholangitis (PSC), are associated with bile stasis and gradually progress to …

Long noncoding RNAs (lncRNAs) are pervasively transcribed in the genome, exhibit a
diverse range of biological functions, and exert effects through a variety of mechanisms. The …